2002年

1. Hagiwara, A., Sano, M., Tanaka, H., Kawabe, M., Tamano, S., Kadota, T., Yanagisawa, T., Maemura, S., Ito, N., Shirai, T.: Lack of enhancing effect of two Kampo medicines, Sho-saiko-to (TJ-9) and Sairei-to (TJ-114), on rat urinary bladder carcinogenesis initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Teratog Carcinog Mutagen, 22: 41-50, 2002.

2. Takahashi, S., Suzuki, S., Inaguma, S., Ikeda, Y., Cho, YM., Nishiyama, N., Fujita, T., Inoue, T., Hioki, T., Sugimura, Y., Ushijima, T., Shirai, T.: Down-regulation of human X-box binding protein 1 (hXBP-1) expression correlates with tumor progression in human prostate cancers. Prostate, 50: 154-161, 2002.

3. Hagiwara, A., Yoshino, H., Ichihara, T., Kawabe, M., Tamano, S., Aoki, H., Koda, T., Nakamura, M., Imaida, K., Ito, N., Shirai, T.: Prevention by natural food anthocyanins, purple sweet potato color and red cabbage color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in rats initiated with 1,2-dimethylhydrazine. J Toxicol Sci, 27: 57-68, 2002.

4. Futakuchi, M., Hirose, M., Imaida, K., Takahashi, S., Ogawa, K., Asamoto, M., Miki, T., Shirai, T.: Chemoprevention of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats. Carcinogenesis, 23: 283-287, 2002.

5. Asamoto, M., Hokaiwado, N., Cho, YM., Shirai, T.: Effects of genetic background on prostate and taste bud carcinogenesis due to SV40 T antigen expression under probasin gene promoter control. Carcinogenesis, 23: 463-467, 2002.

6. Hirose, M., Nishikawa, A., Shibutani, M., Imai, T., Shirai, T.: Chemoprevention of heterocyclic amine-induced mammary carcinogenesis in rats. Environ Mol Mutagen, 39: 271-278, 2002.

7. Futakuchi, M., Cheng, JL., Hirose, M., Kimoto, N., Cho, YM., Iwata, T., Kasai, M., Tokudome, S., Shirai, T.: Inhibition of conjugated fatty acids derived from safflower or perilla oil of induction and development of mammary tumors in rats induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Cancer Lett, 178: 131-139, 2002.

8. Kuroda, H., Ohtsuru, A., Futakuchi, M., Kawashita, Y., Nagayama, Y., Fukuda, E., Namba, H., Shirai, T., Kanematsu, T., Yamashita, S.: Distinctive gene expression of receptor-type tyrosine kinase families during rat hepatocarcinogenesis. Int J Mol Med, 9: 473-480, 2002.

9. Takahashi, S., Suzuki, S., Inaguma, S., Cho, YM., Ikeda, Y., Hayashi, N., Inoue, T., Sugimura, Y., Nishiyama, N., Fujita, T., Ushijima, T., Shirai, T.: Down-regulation of Lsm1 is involved in human prostate cancer progression. Br J Cancer, 86: 940-946, 2002.

10. Takahashi, S., Inaguma, S., Cho, YM., Imaida, K., Wang, J., Fujiwara, O., Shirai, T.: Lack of mutation induction with exposure to 1.5 GHz electromagnetic near fields used for cellular phones in brains of Big Blue mice. Cancer Res, 62: 1956-1960, 2002.

11. Williams, GM., Iatropoulos, MJ., Jeffrey, AM., Shirai, T.: Protective effect of acetaminophen against colon cancer initiation effects of 3,2′-dimethyl-4-aminobiphenyl in rats. Eur J Cancer Prev, 11: 39-48, 2002.

12. Takahashi, S., Inaguma, S., Sakakibara, M., Cho, YM., Suzuki, S., Ikeda, Y., Cui, L., Shirai, T.: DNA methylation in the androgen receptor gene promotor region in rat prostate cancer, Prostate, 52: 82-88, 2002.

13. Inoue, T., Hioki, T., Hayashi, N., Takahashi, S., Shirai, T., Sugimura, Y.: Preoperative predictors of cancerous involvement of the neurovascular bundles in patients with localized prostate cancer. Int J Urol, 9: 47-53, 2002.

14. Tamano, S., Sano, M., Kawabe, M., Hagiwara, A., Nakamura, M., Imaida, K., Shirai, T.: Purple sweet potato color lacks tumor promoting or carcinogenic potential in a medium-term multi-organ carcinogenesis bioassay in male rats. Jpn J Fd Chem, 9: 22-29, 2002.

15. Ito, N.: Genetically modified foods: Hazard identification and risk assessment. Exp Toxicol Pathol, 54: 57-59, 2002.

16. Asamoto, M., Hokaiwado, N., Cho, YM., Shirai, T.: A transgenic rat model of prostate carcinogenesis, J Toxicol Pathol, 15: 191-196, 2002.

17. Fukushima, S., Wanibuchi, H., Morimura, K., Wei, M., Nakae, D., Konishi, Y., Tsuda, H., Uehara, N., Imaida, K., Shirai, T., Tatematsu, M., Tsukamoto, T., Hirose, M., Furukawa, F., Wakabayashi, K., Totsuka, Y.: Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine. Jpn J Cancer Res, 93: 1076-1082, 2002.

18. Futakuchi, M., Ogawa, K., Sano, M., Tamano, S., Takeshita, F., Shirai, T.: Suppression of lung metastasis by aspirin but not indomethacin in an in vivo model of chemically induced hepatocellular carcinoma. Jpn J Cancer Res, 93: 1175-1181, 2002.

19. Shirai, T., Kato, K., Futakuchi, M., Takahashi, S., Suzuki, S., Imaida, K., Asamoto, M.: Organ differences in the enhancing potential of 2-amino-1-methy-6-phenylimidazo[4,5-b]pyridine on carcinogenicity in the prostate, colon and pancreas. Mutat Res, 506-507: 129-136, 2002.

20. Suzuki, S., Takahashi, S., Asamoto, M., Inaguma, S., Ogiso, T., Hirose, M., Shirai, T.: Lack of modification of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis in rats by fenbendazole – a CYP1A2 inducer. Cancer Lett, 185: 39-45, 2002.

21. Yoshino, H., Ichihara, T., Kawabe, M., Imai, N., Hagiwara, A., Asamoto, M., Shirai, T. Lack of significant alteration in the prostate or testis of F344 rat offspring after transplacental and lactational exposure to bisphenol A. J Toxicol Sci, 27: 433-439, 2002.

22. Hirose, M., Yamaguchi, T., Mizoguchi, Y., Akagi, K., Futakuchi, M., Shirai, T.: Lack of inhibitory effects of green tea catechins in 1,2-dimetylhydrazine-induced rat intestinal carcinogenesis model: comparison of the different formulations, administration routes and doses. Cancer Lett, 188: 163-170, 2002.

23. Shirai, T., Asamoto, A., Takahashi, S., Imaida, K.: Diet and prostate cancer. Toxicology, 181-182: 89-94, 2002.

24. Yada, H., Hirose, M., Tamano, S., Kawabe, M., Sano, M., Takahashi, S., Futakuchi, M., Miki, T., Shirai, T.: Effects of antioxidant 1-O-hexyl-2,3,5-trimethylhydroquinone or ascorbic acid on carcinogenesis induced by administration of aminopyrine and sodium nitrite in a rat multi-organ carcinogenesis model. Jpn J Cancer Res, 93: 1299-1307, 2002.

25. Fujiwara, H., Emi, M., Nagai, H., Nishimura, T., Konishi, N., Kubota, Y., Ichikawa, T., Takahashi, S., Shuin, T., Habuchi, T., Ogawa, O., Inoue, K., Skolnick, MH., Swensen, J., Camp, NJ., Tavtigian, SV.: Association of common missense changes in ELAC2 (HPC2) with prostate cancer in a Japanese case-control series. J Hum Genet, 47: 641-648, 2002.

26. 二口充、小川久美子、関健司:厚生院における病理解剖 (XXI). 名古屋市厚生院紀要, 28: 75-84, 2002.

27. 二口充、彦坂敦也、白井智之:造骨性変化を伴うラット前立腺癌骨浸潤モデルを用いた抗Parathyroid related peptide (PTHrP)中和抗体の抑制作用の検討. 名古屋市厚生院紀要, 28: 29-36, 2002.