1993年

1. Shirai, T., Imaida, K., Iwasaki, S., Mori, T., Tada, M., Ito, N.: Sequential observation of rat prostate lesion development induced by 3,2′-dimethyl-4-aminobiphenyl and testosterone. Jpn J Cancer Res, 84: 20-25, 1993.

2. Hirose, M., Tanaka, H., Takahashi, S., Futakuchi, M., Fukushima, S., Ito, N.: Effects of sodium nitrite and catechol, 3-methoxycatechol, or butylated hydroxyanisole in combination in a rat multiorgan carcinogenesis model. Cancer Res, 53: 32-37, 1993.

3. Thamavit, W., Moore, MA., Sirisinha, S., Shirai, T., Ito, N.: Time-dependent modulation of liver lesion development in Opisthorchis-infected Syrian hamster by an antihelminthic drug, praziquantel. Jpn J Cancer Res, 84: 135-138, 1993.

4. Shibata, MA., Hirose, M., Kagawa, M., Boonyaphiphat, P., Ito, N.: Enhancing effect of concomitant L-ascorbic acid administration on BHA-induced forestomach carcinogenesis in rats. Carcinogenesis, 14: 275-280, 1993.

5. Mizoguchi, M., Naito, H., Kurata, Y., Shibata, MA., Tsuda, H., Wild, CP., Montesano, R., Fukushima, S.: Influence of aging on multi-organ carcinogenesis in rats induced by N-methyl-N-nitrosourea. Jpn J Cancer Res, 84: 139-146, 1993.

6. Tamano, S., Kawabe, F., Sano, M., Masui, T., Ito, N.: Subchronic oral toxicity study of captafol in B6C3F1 mice. J Toxicol Environ Health, 38: 69-75, 1993.

7. Hagiwara, A., Tanaka, H., Imaida, K., Tamano, S., Fukushima, S., Ito, N.: Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats. Jpn J Cancer Res, 84: 237-245, 1993.

8. Hirose, M., Fukushima, S., Tanaka, H., Asakawa, E., Takahashi, S., Ito, N.: Carcinogenicity of catechol in F344 rats and B6C3F1 mice. Carcinogenesis, 14: 525-529, 1993.

9. Shibata, MA., Shirai, T., Asakawa, E., Hirose, M., Fukushima, S.: Inhibition by dehydroepiandrosterone of butylated hydroxyanisole (BHA) promotion of rat-bladder carcinogenesis and enhancement of BHA-induced forestomach hyperplasia. Int J Cancer, 53: 819-823, 1993.

10. Hirose, M., Akagi, K., Hasegawa, R., Satoh, T., Nihro, Y., Miki, T., Sugimura, T., Ito, N.: Strong inhibition of 2-amino-6-methyldipyrido[1,2-a: 3′, 2′-d]imidazole-induced mutagenesis and hepatocarcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone. Jpn J Cancer Res, 84: 481-484, 1993.

11. Tamano, S., Tanaka, H., Kawabe, M., Asakawa, E., Sano, M., Shioya, S., Shirai, T., Fukushima, S.: No enhancing effects of calcium / magnesium salts of L-glutamate and L-ascorbate on tumor development in a rat medium-term multiorgan carcinogenesis bioassay. J Toxicol Environ Health, 39: 43-58, 1993.

12. Toyoda, K., Imaida, K., Shirai, T., Imazawa, T., Takahashi, M.: Relationship between bisacodyl-induced urolithiasis and rat urinary bladder tumorigenesis. J Toxicol Environ Health, 39: 59-78, 1993.

13. Hasegawa, R., Cabral, R., Hoshiya, T., Hakoi, K., Ogiso, T., Boonyaphiphat, P., Shirai, T., Ito, N.: Carcinogenic potential of some pesticides in a medium-term multi-organ bioassay in rats. Int J Cancer, 54: 489-493, 1993.

14. Suzuki, S., Tamura, Y., Takazawa, Y., Mashimo, T., Imai, K., Yuasa, H., Yamanaka, H., Shirai, T.: Ultrasonic diagnosis of 3,2′-dimethyl-4-aminobiphenyl induced tumors in the urogenital organs of F344 rats. Prostate, 22: 235-241, 1993.

15. Tatematsu, M., Ichinose, M., Tsukada, S., Kakei, N., Takahashi, S., Ogawa, K., Hirose, M., Furihata, C., Miki, K., Kurokawa, K., Ito, N.: DNA methylation of the pepsinogen 1 gene during rat glandular stomach carcinogenesis induced by N-methyl-N’-nitro-N-nitrosoguanidine or catechol. Carcinogenesis, 14: 1415-1419, 1993.

16. Shibata, MA., Hirose, M., Masuda, A., Kato, T., Mutai, M., Ito, N.: Modification of BHA forestomach carcinogenesis in rats: inhibition by diethylmaleate or indomethacin and enhancement by a retinoid. Carcinogenesis, 14: 1265-1269, 1993.

17. Tamano, S., Asakawa, E., Boonyaphiphat, P., Masui, T., Fukushima, S.: Lack of promotion of N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated urinary bladder carcinogenesis in mice by rat cancer promoters. Teratog Carcinog Mutagen, 13: 89-96, 1993.

18. Kurata, Y., Diwan, BA., Uno, H., Rice, JM., Ward. JM.: Pathology of preneoplastic and neoplastic renal tubular lesions induced in F-344 rats by sodium barbital, a nongenotoxic renal carcinogen and nephrotoxin. Toxicol Pathol, 21: 35-45, 1993.

19. Shrai, T.: Etiology of bladder cancer. Semin Urol, 11: 113-126, 1993.

20. Shibata, MA., Sano, M., Shirai, T., Imaida, K., Fukushima, S.: Epithelial hyperplasia in the renal papilla and pelvis but not the urinary bladder of male F344 rats associated with dietary sodium phosphates after uracil exposure. Toxicol Appl Pharmacol, 121: 303-312, 1993.

21. Okazaki, S., Hoshiya, T., Takahashi, S., Futakuchi, M., Saito, K., Hirose, M.: Modification of hepato- and renal carcinogenesis by catechol and its isomers in rats pretreated with N-ethyl-N-hydroxyethylnitrosamine. Teratog Carcinog Mutagen, 13: 127-137, 1993

22. Hirose, M., Hoshiya, T., Akagi, K., Takahashi, S., Hara, Y., Ito, N.: Effects of green tea catechins in a rat multi-organ carcinogenesis model. Carcinogenesis, 14: 1549-1553, 1993.

23. Tatematsu, M., Iwata, H., Ichinose, M., Kakei, N., Tsukada, S., Miki, K., Imai, S., Imaida, K.: Markers of surface mucous cell type human gastric cancer cells: Galactose oxidase-Schiff reactive mucins, monoclonal antibody SH-9 reactive mucins and cathepsin E. Acta Pathol Jpn, 43: 500-506, 1993.

24. Kawabe, M., Tamano, S., Shibata, MA., Hirose, M., Fukushima, S., Ito, N.: Subchornic toxicity study of methyl hesperidin in mice. Toxicol Lett, 69: 37-44, 1993.

25. Hoshiya, T., Hasegawa, R., Hakoi, K., Cui, L., Ogiso, T., Cabral, R., Ito, N.: Enhancement by non-mutagenic pesticides of GST-P positive hepatic foci development initiated with diethylnitrosamine in the rat. Cancer Lett, 72: 59-64, 1993.

26. Hagiwara, A., Ogiso, T., Shibata, MA., Shirai, T.: Spontaneous pleomorphic adenoma in the submandibular salivary gland of an aged male (C57BL/6N×C3H/HeN) F1 (B6C3F1) mouse. Vet Pathol, 30: 394-396, 1993.

27. Tiwawech, D., Siripong, P., Kupradinun, P., Thamavit, W., Shirai, T., Hagiwara, A., Ito, N.: Inhibition of diethylnitrosamine (DEN)-induced hepatic foci by pre and post treatment with Acanthus ebracteatus Vahl. in rats. Thai Cancer J, 19: 7-13, 1993.

28. Shirai, T., Iwasaki, S., Masui, T., Mori, T., Kato, T., Ito, N.: Enhancing effect of cadmium on rat ventral prostate carcinogenesis induced by 3,2′-dimethyl-4-aminobiphenyl. Jpn J Cancer Res, 84: 1023-1030, 1993.

29. Kagawa, M., Hakoi, K., Yamamoto, A., Futakuchi, M., Hirose, M.: Comparison of reversibility of rat forestomach lesions induced by genotoxic and non-genotoxic carcinogens. Jpn J Cancer Res, 84: 1120-1129, 1993.

30. Takahashi, S., Shirai, T., Ogawa, K., Imaida, K., Yamazaki, C., Ito, A., Masuko, K., Ito, N.: Renal cell adenomas and carcinomas in hemodialysis patients: Relationship between hemodialysis period and development of lesions. Acta Pathol Jpn, 43: 674-682, 1993.

31. Hirose, M., Yada, H., Hakoi, K., Takahashi, S., Ito, N.: Modification of carcinogenesis by α-tocopherol, t-butylhydroquinone, propyl gallate and butylated hydroxytoluene in a rat multi-organ carcinogenesis model. Carcinogenesis, 14: 2359-2364, 1993.

32. Thamavit, W., Pairojkul, C., Tiwawech, D., Itoh, M., Shirai, T., Ito, N.: Promotion of cholangiocarcinogenesis in the hamster liver by bile duct ligation after dimethylnitrosamine initiation. Carcinogenesis, 14: 2415-2417, 1993.

33. Yamaguchi, S., Hakoi, K., Ozaki, K., Kato, T., Tiwawech, D., Nagao, S., Takahashi, H., Matsumoto, K., Tsuda, H.: Number of simultaneously expressed enzyme alterations correlates with progression of N-ethyl-N-hydroxyethylnitrosamine-induced hepatocarcinogenesis in rat. Jpn J Cancer Res, 84: 1237-1244, 1993.

34. Ozaki, K., Kato, T., Asamoto, M., Wild, CP., Montesano, R., Nagao, S., Iwase, T., Matsumoto, K., Tsuda, H.: Decreased dimethylnitrosamine-induced O6-and N7-methy1deoxyguanosine levels correlate with development and progression of lesions in rat hepatocarcinogenesis. Jpn J Cancer Res, 84: 1245-1251, 1993.

35. Kato, T., Imaida, K., Ogawa, K., Hasegawa, R., Shirai, T., Tatematsu, M.: Three-dimensional analysis of glutathione S-transferase placental form-positive lesion development in early stages of rat hepatocarcinogenesis. Jpn J Cancer Res, 84: 1252-1257, 1993.

36. de Camargo, JLV., Tsuda, H., Asamoto, M., Tagawa, Y., Wada, S., Nagase, S., Ito, N.: Modifying effects of chemicals on the development of liver preneoplastic placental glutathione S-transferase positive foci in analbuminemic and Sprague-Dawley rats. Toxicol Pathol, 21: 409-416, 1993.

37. Shibata, MA., Hasegawa, R., Shirai, T., Takesada, Y., Fukushima, S.: Chemoprevention by indomethacin of tumor promotion in a rat urinary bladder carcinogenesis model. Int J Cancer, 55: 1011-1017, 1993.

38. Hagiwara, A., Tiwawech, D., Imaida, K., Tamano, S., Shibata, MA., Fukushima, S., Ito, N.: Modifying influence of prior treatment with toxic agents on induction of preneoplastic and neoplastic lesions in a medium-term multi-organ carcinogenesis bioassay. Teratog Carcinog Mutagen, 13: 277-287, 1993.

39. Yoshida, Y., Tatematsu, M., Takaba, K., Iwasaki, S., Ito, N.: Target organ specificity of cell proliferation induced by various carcinogenesis. Toxicol Pathol, 21: 436-442, 1993.

40. Hasegawa, R., Sano, M., Tamano, S., Imaida, K., Shirai, T., Nagao, M., Sugimura, T., Ito, N.: Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) carcinogenicity in rats. Carcinogenesis, 14: 2553-2557, 1993.

41. Shibata, MA., Kurata, Y., Hagiwara, A., Shirai, T., Fukushima, S: Lack of tumorigenic effects on rat renal pelvic transitional epithelium of lifespan exposure to low doses of a bladder carcinogen. J Toxicol Pathol, 6: 47-53, 1993.

42. Ito, N., Hirose, M., Takahashi, S.: Cell proliferation and forestomach carcinogenesis. Environ Health Perspect, 101: 107-110, 1993.

43. Ito, N., Hasegawa, R., Cabral, JRP.: Medium-term in vivo bioassays for carcinogenicity of pesticides. In: Roe, RM. & Kuhr, RJ. (eds.) Rev Pestic Toxicol, 2, pp115-132: Toxicology Communications Inc., Raleigh, NC, 1993.

44. Hirose, M., Shirai, T., Takahashi, S., Ogawa, K., Ito, N.: Organ-specific modification of carcinogenesis by antioxidants in rats. In: Bronzetti, G., et al.(eds.) Antimutagenesis and Anticarcinogenesis Mechanisms III, pp 181-188. Plenum Press, New York, 1993.

45. 田川義章:3,2′-dimethyl-4-aminobiphenyl (DMAB) によるラット前立腺発癌における系統差ならびに脂質の発癌修飾作用. 名古屋市立大学医学会雑誌, 44: 87-103, 1993.

46. 内藤初美:カフェ酸によるラット前胃発癌ならびに発癌促進作用に関する実験的解析. 名古屋市立大学医学会雑誌, 44: 105-120, 1993.

47. 宇和川賢:化学物質の発癌性検索のための他臓器中期発癌性試験法の検討. 名古屋市立大学医学会雑誌, 44: 61-86, 1993.

48. 白井智之, 高橋智:前立腺異型過形成. 前がん病変としての意義. CRC, 2: 164-171, 1993.

49. 長谷川良平, 今井田克己, 増井恒夫, 小川久美子, 加藤俊男, 伊東信行:ラット肝中期発がん性試験法の有用性と応用. 変異原性試験, 2: 1-10, 1993.

50. 片岡洋望, 勝見康平, 中沢貴宏, 池戸昌秋, 竹島彰彦, 坂義満, 伊藤龍雄, 岸本明比古, 加藤實, 柴田純孝, 渡辺晋, 白井智之:下行結腸に穿孔を生じた小腸・大腸クローン病の1例. 本邦報告例19例の検討. 消化器内視鏡, 5: 427-432, 1993.

51. 坂野章吾, 仁田正和, 高田勝利, 長谷川良平, 新美達司, 山本俊幸:肺腫瘤で発症し多彩な免疫異常を合併した高齢者非ホジキンリンパ腫の1例. 日本老年医学会雑誌, 30: 506-510, 1993.

52. 井上忠志:o-PhenylphenolおよびそのNa塩のラット膀胱発癌性に関する病理学的研究. 名古屋市立大学医学会雑誌, 44: 463-477, 1993.

53. 橋本俊, 由良二郎, 清水保延, 中村司, 音部好宏, 山守暢子, 林周作, 小野雅之, 田中守嗣, 花井拓美, 白井智之, 河原崎秀雄, 松波英寿:生体肝移植の周術期における免疫抑制と拒絶反応の診断. 移植, 28: 571-579, 1993.

54. 津田洋幸, 松本和幸, 高橋智, 岡村武彦:腎細胞種の形質表現の特異性と組織発生の解析. 病理と臨床, 11: 1105-1110, 1993.

55. 務台衛:ラット肝発癌過程における肝発癌物質・発癌修飾物質の低用量複合曝露の影響の解析. 名古屋市立大学医学会雑誌, 44: 525-548, 1993.

56. 中村厚:ラットにおける3,2′-dimethyl-4-aminobiphenyl(DMAB)の臓器発癌性とDNA付加体形成との関連性に関する研究. 名古屋市立大学医学会雑誌, 44: 549-563, 1993.

57. 田中光:Harmanおよびnorharman によるラット腎障害作用ならびに発癌促進作用に関する実験的解析. 名古屋市立大学医学会雑誌, 44: 565-584, 1993.

58. 今井田克巳, 加藤俊男, 長谷川良平, 鈴木幹三, 松浦徹, 山本俊幸:高齢者剖検例にみられた肺腫瘍の病理学的検討. 名古屋市厚生院紀要, 19: 26-33, 1993.

59. 伊藤寛, 江口武史, 全並秀司, 成田清, 堀内格, 本田英邦, 渡辺勇, 坂上充志, 高橋智, 福島昭治 : Malignant rhabdoid tumor of the kidney (MRTK) の1例.日本小児外科学会雑誌, 29: 1266-1272, 1993.

60. 橋本俊, 清水保延, 中村司, 音部好宏, 山守暢子, 伊藤浩一, 林周作, 小野雅之, 田中守嗣, 花井拓美, 白井智之:生体肝移植における免疫制御. 現代医学, 41: 227-233, 1993.

61. 成田清, 伊藤寛, 全並秀司, 江口武史, 本多英邦, 今井田克己:長期透析患者に発症した壊死型虚血性腸炎の1例. 名古屋市立病院紀要, 16: 85-87, 1993.

62. 伊藤寛, 全並秀司, 江口武史, 成田清, 本多英邦, 渡辺勇, 大内正信, 今井田克己 : メッケル憩室による乳児紋扼性腸閉塞症の一例. 名古屋市立病院紀要, 16: 81-84, 1993.