1. Shirai, T., Takahashi, S., Cui, L., Yamada, Y., Tada, M., Kadlubar, FF., Ito, N.: Use of polyclonal antibodies against carcinogen-DNA adducts in analysis of carcinogenesis. Toxicol Lett, 102-103: 441-446, 1998.

2. Cui, L., Mori, T., Takahashi, S., Imaida, K., Akagi, K., Yada, H., Yaono, M., Shirai, T.: Slight promotion effects of intermittent administration of testosterone propionate and/or diethylstilbestrol on 3,2′-dimethyl-4-aminobiphenyl-initiated rat prostate carcinogenesis. Cancer Lett, 122: 195-199, 1998.

3. Tsukamoto, S., Akaza, H., Onozawa, M., Shirai, T., Ideyama, Y.: A five-alpha reductase inhibitor or an antiandrogen prevents the progression of microscopic prostate carcinoma to macroscopic carcinoma in rats. Cancer, 82: 531-537, 1998.

4. Hasegawa, R., Futakuchi, M., Mizoguchi, Y., Yamaguchi, T., Shirai, T., Ito, N., Lijinsky, W.: Studies of initiation and promotion of carcinogenesis by N-nitroso compounds. Cancer Lett, 123: 185-191, 1998.

5. Imaida, K., Taki, M., Yamaguchi, T., Ito, T., Watanabe, S., Wake, K., Aimoto, A., Kamimura, Y., Ito, N., Shirai, T.: Lack of promoting effects of the electromagnetic near-field used for cellular phones (929.2 MHz) on rat liver carcinogenesis in a medium-term liver bioassay. Carcinogenesis, 19: 311-314, 1998.

6. Wada, S., Hirose, M., Shichino, Y., Ozaki, K., Hoshiya, T., Kato, K., Shirai, T.: Effects of catechol, sodium chloride and ethanol either alone or in combination on gastric carcinogenesis in rats pretreated with N-methyl-N’-nitro-N-nitrosoguanidine. Cancer Lett, 123: 127-134, 1998.

7. Hirose, M., Takesada, Y., Tanaka, H., Tamano, S., Kato, T., Shirai, T.: Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and catechol at low doses, either alone or in combination, and modulation of their effects in a rat medium-term multi-organ carcinogenesis model. Carcinogenesis, 19: 207-212, 1998.

8. Ogawa, K., Iwasaki, S., Esumi, H., Fukushima, S., Shirai, T.: Modification by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) of 3,2′-dimethyl-4-aminobiphenyl (DMAB)-induced rat pancreatic and intestinal tumorigenesis. Cancer Lett, 124: 31-37, 1998.

9. Takahashi, S., Hirose, M., Tamano, S., Ozaki, M., Orita, S., Ito, T., Takeuchi, M., Ochi, H., Fukada, S., Kasai, H., Shirai, T.: Immunohistochemical detection of 8-hydroxy-2′-deoxyguanosine in paraffin-embedded sections of rat liver after carbon tetrachloride treatment. Toxicol Pathol, 26: 247-252, 1998.

10. Kato, K., Takahashi, S., Mori, T., Futakuchi, M., Cui, L., Ito, N., Shirai, T.: Establishment of transplantable rat prostate carcinomas from primary lesions induced by 3,2′-dimethyl-4-aminobiphenyl and testosterone. J Toxicol Pathol, 11: 27-32, 1998.

11. Futakuchi, M., Hirose, M., Miki, T., Tanaka, H., Ozaki, M., Shirai, T.: Inhibition of DMBA-initiated rat mammary tumour development by 1-O-hexyl-2,3,5-trimethylhydroquinone, phenylethyl isothiocyanate, and novel synthetic ascorbic acid derivatives. Eur J Cancer Prev, 7: 153-159, 1998.

12. Kato, T., Hirose, M., Takahashi, S., Hasegawa, R., Kohno, T., Nishibe, S., Kato, K., Shirai, T.: Effects of the lignan, arctiin, on 17-β ethinyl estradiol promotion of preneoplastic liver cell foci development in rats. Anticancer Res, 18: 1053-1058, 1998.

13. Mizoguchi, Y., Hirose, M., Yamaguchi, T., Boonyaphiphat, P., Miki, T., Shirai, T.: Dose dependence of 1-O-hexyl-2,3,5-trimethylhydroquinone promotion of forestomach carcinogenesis in rats pretreated with N-ethylnitrosourethane., Jpn J Cancer Res, 89: 475-480, 1998.

14. Hirose, M., Futakuchi, M., Tanaka, H., Orita, SI., Ito, T., Miki, T., Shirai, T.: Prevention by antioxidants of heterocyclic amine-induced carcinogenesis in a rat medium-term liver bioassay: results of extended and combination treatment experiments. Eur J Cancer Prev, 7: 61-67, 1998.

15. Ogawa, K., Futakuchi, M., Hirose, M., Boonyaphiphat, P., Mizoguchi, Y., Miki, T., Shirai, T.: Stage and organ dependent effects of 1-O-hexyl-2,3,5-trimethylhydroquinone, ascorbic acid derivatives, n-heptadecane-8,10- dione and phenylethyl isothiocyanate in a rat multiorgan carcinogenesis model. Int J Cancer, 76: 851-856, 1998.

16. Tamano, S., Hirose, M., Tanaka, H., Hagiwara, A., Shirai, T.: Variation in susceptibility to the induction of forestomach tumours by butylated hydroxyanisole among rats of different strains. Fd Chem Toxicol, 36: 299-304, 1998.

17. Hirose, M., Ito, T., Takahashi, S., Ozaki, M., Ogiso, T., Nihro, Y., Miki, T., Shirai, T.: Prevention by synthetic phenolic antioxidants of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)- or activated MeIQx-induced mutagenesis and MeIQx-induced rat hepatocarcinogenesis, and role of antioxidant activity in the prevention of carcinogenesis. Eur J Cancer Prev, 7: 233-241, 1998.

18. Asamoto, M., Hori, T., Baba-Toriyama, H., Sano, M., Takahashi, S., Tsuda, H., Shirai, T.: p16 gene overexpression in mouse bladder carcinomas. Cancer Lett, 127: 9-13, 1998.

19. Hirose, M., Yamaguchi, T., Kimoto, N., Ogawa, K., Futakuchi, M., Sano, M., Shirai, T.: Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats. Int J Cancer, 77: 773-777, 1998.

20. Lucia, MS., Bostwick, DG., Bosland, M., Cockett, AT., Knapp, DW., Leav, I., Pollard, M., Rinker-Schaeffer, C., Shirai, T., Watkins, BA.: Workgroup I: Rodent models of prostate cancer. Prostate, 36: 49-55, 1998.

21. Takahashi, S., Kimoto, N., Orita, S., Cui, L., Sakakibara, M., Shirai, T.: Relationship between CD44 expression and differentiation of human prostate adenocarcinomas. Cancer Lett, 129: 97-102, 1998.

22. Yamada, Y., Tozawa, K., Cui, L., Takahashi, S., Shirai, T., Kohri, K.: Characteristics of nonneoplastic human prostate tissue transplanted into nude mice. Prostate, 37: 109-115, 1998.

23. Kitano, M., Ichihara, T., Matsuda, T., Wanibuchi, H., Tamano, S., Hagiwara, A., Imaoka, S., Funae, Y., Shirai, T., Fukushima, S.: Presence of a threshold for promoting effects of phenobarbital on diethylnitrosamine-induced hepatic foci in the rat. Carcinogenesis, 19: 1475-1480, 1998.

24. Takahashi, S., Tamano, S., Hirose, M., Kimoto, N., Ikeda, Y., Sakakibara, M., Tada, M., Kadlubar, FF., Ito, N., Shirai, T.: Immunohistochemical demonstration of carcinogen-DNA adducts in tissues of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Detection in paraffin-embedded sections and tissue distribution. Cancer Res, 58: 4307-4313, 1998.

25. Zhang, R., Takahashi, S., Orita, S., Yoshida, A., Maruyama, H., Shirai, T., Ohta, N.: p53 gene mutations in rectal cancer associated with schistosomiasis japonica in Chinese patients. Cancer Lett, 131: 215-221, 1998.

26. Imaida, K., Taki, M., Watanabe, S., Kamimura, Y., Ito, T., Yamaguchi, T., Ito, N., Shirai, T.: The 1.5 GHz electromagnetic near-field used for cellular phones does not promote rat liver carcinogenesis in a medium-term liver bioassay. Jpn J Cancer Res, 89: 995-1002, 1998.

27. Ito, N., Imaida, K., Tamano, S., Hagiwara, A., Shirai, T.: Medium-term bioassays as alternative carcinogenicity test. J Toxicol Sci, 23 Suppl 2: 103-106, 1998.

28. Hashimoto, Y., Suzuki, T., Shimizu, Y., Otobe, Y., Nakamura, T., Nakamura, Y., Tanaka, M., Ito, K., Ueda, N., Hayashi, S., Manabe, T., Futakuchi, M., Shirai, T.: ABO-incompatible living related liver transplantation for fulminant hepatitis: report of a successful pediatric case with long-term follow-up. Transplant Proc, 30: 3510-3512, 1998.

29. Ito, N., Imaida, K., Hirose, M., Shirai, T.: Medium-term bioassays for carcinogenicity of chemical mixtures. Environ Health Perspect, 106 Suppl 6: 1331-1336, 1998.

30. Bosland, MC., Tuomari, DL., Elwell, MR., Shirai, T., Ward, JM., McConnel, RF.: Proliferative lesions of the prostate and other accessory sex glands in male rats. In: Guides for Toxicologic Pathology, pp1-20. STP/ARP/AFIP, Washington, DC, 1998.

31. Ito, N., Imaida, K., Hagiwara, A., Tamano, S., Shirai, T.: Effects of ingesting a combination of 20 or 40 pesticides at ADI levels on carcinogenesis in rats. In: Reviews in Toxicology 2, pp85-92, IOS Press, 1998.