1. Tatematsu, M., Lurie, AG., Rippey, RM., Conran, PB., Arai, M., Fukushima, S., Ito, N.: Possible mechanistic roles of anatomical and functional vascular changes in rat urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine. Cancer Res, 44: 278-284, 1984.

2. Ito, N., Moore, MA., Bannasch, P.: Modification of the development of N-nitrosomorpholine-induced hepatic lesions by 2-acetylaminofluorene, phenobarbital and 4,4′-diaminodiphenylmethane: a sequential histological and histochemical analysis. Carcinogenesis, 5: 335-342, 1984.

3. Furihata, C., Tatematsu, M., Miki, K., Katsuyama, T., Sudo, K., Miyagi, N., Kubota, T., Jin, SS., Kodama, K., Ito, N., Konishi, Y., Suzuki, K., Matsushima, T.: Gastric- and intestinal-type properties of human gastric cancers transplanted into nude mice. Cancer Res, 44: 727-733, 1984.

4. Shirai, T., Arai, M., Sakata, T., Fukushima, S., Ito, N.: Primary carcinomas of urinary bladder diverticula. Acta Pathol Jpn, 34: 417-424, 1984.

5. Tsuda, H., Nakanishi, K., Hatano, A., Okumura, M., Seki, K.: Summational effect of three different hepatopromoters in rats after initiation with diethylnitrosamine. Nagoya Med J, 28: 171-182, 1984.

6. Shirai, T., Ohshima, M., Masuda, A., Tamano, S., Ito, N.: Promotion of 2-(ethylnitrosamino)- ethanol-induced renal carcinogenesis in rats by nephrotoxic compounds: Positive responses with folic acid, basic lead acetate, and N-(3,5-dichlorophenyl)succinimide but not with 2,3-dibromo-1-propanol phosphate. J Natl Cancer Inst, 72: 477-482, 1984.

7. Tsuda, H., Sakata, T., Masui, T., Imaida, K., Ito, N.: Modifying effects of butylated hydroxyanisole, ethoxyquin and acetaminophen on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine. Carcinogenesis, 5: 525-531, 1984.

8. Sato, K., Kitahara, A., Satoh, K., Ishikawa, T., Tatematsu, M., Ito, N.: The placental form of glutathione S-transferase as a new marker protein for preneoplasia in rat chemical hepatocarcinogenesis. Gann, 75: 199-202, 1984.

9. Yanagi, S., Tsuda, H., Sakamoto, M., Fuse, E., Ito, N.: Effects of margarine on hepatocarcinogenesis by N,N’-2,7-fluorenylenebisacetamide in mice. Oncology, 41: 101-105, 1984.

10. Sato, K., Kitahara, A., Yin, Z., Waragai, F., Nishimura, K., Hatayama, I., Ebina, T., Yamazaki, T., Tsuda, H., Ito, N.: Induction by butylated hydroxyanisole of specific molecular forms of glutathione S-transferase and UDP-glucuronyltransferase and inhibition of development of γ-glutamyl transpeptidase-positive foci in rat liver. Carcinogenesis, 5: 473-477, 1984.

11. Shirai, T., Fukushima, S., Ohshima, M., Masuda, A., Ito, N.: Effects of butylated hydroxyanisole, butylated hydroxytoluene, and NaCl on gastric carcinogenesis initiated with N-methyl-N’-nitro-N-nitrosoguanidine in F344 rats. J Natl Cancer Inst, 72: 1189-1198, 1984.

12. Ito, N., Hirose, M., Kurata, Y., Ikawa, E., Mera, Y., Fukushima, S.: Induction of forestomach hyperplasia by crude butylated hydroxyanisole, a mixture of 3-tert and 2-tert isomers, in syrian golden hamsters is due to 3-tert-butylated hydroxyanisole. Gann, 75: 471-474, 1984.

13. Shirai, T., Kurata, Y., Fukushima, S., Ito, N.: Dose-related induction of lung, thyroid and kidney tumors by N-bis(2-hydroxypropyl)nitrosamine given orally to F344 rats. Gann, 75: 502-507, 1984.

14. Fukushima, S., Kurata, Y., Shibata, MA., Ikawa, E., Ito, N.: Promotion by ascorbic acid, sodium erythorbate and ethoxyquin of neoplastic lesions in rats initiated with N-butyl-N-(4-hydroxybutyl) nitrosamine. Cancer Lett, 23: 29-37, 1984.

15. Kitahara, A., Satoh, K., Nishimura, K., Ishikawa, T., Ruike, K., Sato, K., Tsuda, H., Ito, N.: Changes in molecular forms of rat hepatic glutathione S-transferase during chemical hepatocarcinogenesis. Cancer Res, 44: 2698-2703, 1984.

16. Miyata, Y., Fukushima, S., Imaida, K., Ito, N.: Promoting effects of unilateral ureteric ligation on two-stage urinary bladder carcinogenesis in rats. Cancer Lett, 23: 265-272, 1984.

17. Tsuda, H., Sakata, T., Shirai, T., Kurata, Y., Tamano, S., Ito, N.: Modification of N-methyl-N-nitrosourea initiated carcinogenesis in the rat by subsequent treatment with antioxidants, phenobarbital and ethinyl estradiol. Cancer Lett, 24: 19-27, 1984.

18. Ito, N., Shirai, T., Fukushima, S., Hirose, M.: Dose-response study of urinary bladder carcinogenesis in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine. J Cancer Res Clin Oncol, 108: 169-173, 1984.

19. Sato, A., Nakajima, T., Koyama, Y., Shirai, T., Ito, N.: Dietary carbohydrate level as a modifying factor of 3′-methyl-4-dimethylaminoazobenzene liver carcinogenesis in rats. Gann, 75: 665-671, 1984.

20. Tsuda, H., Fukushima, S., Imaida, K., Sakata, T., Ito, N.: Modification of carcinogenesis by antioxidants and other compounds. Acta Pharmacol Toxicol, 55: 125-143, 1984.

21. Tsuda, H., Tamano, S., Imaida, K., Ohshima, M., Kitahori, Y., Ito, N.: Three-dimensional observations by scanning electron microscopy on the blood supply and organization of vasculature during hepatocarcinogenesis in rats. Acta Pathol Jpn, 34: 957-970, 1984.

22. Hagiwara, A., Fukushima, S., Kitaori, M., Shibata, M., Ito, N.: Effects of three sweeteners on rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 75: 763-768, 1984.

23. Imaida, K., Fukushima, S., Shirai, T., Masui, T., Ogiso, T., Ito, N.: Promoting activities of butylated hydroxyanisole, butylated hydroxytoluene and sodium L-ascorbate on forestomach and urinary bladder carcinogenesis initiated with methylnitrosourea in F344 male rats. Gann, 75: 769-775, 1984.

24. Hagiwara, A., Shibata, M., Hirose, M., Fukushima, S., Ito, N.: Long-term toxicity and carcinogenicity study of sodium o-phenylphenate in B6C3F1 mice. Fd Chem Toxicol, 22: 809-814, 1984.

25. Tsuda, H., Takano, T., Shirai, T., Suzuki, M., Baba, S., Ito, N.: Comparative light and scanning electron microscopic observations of nasal cavity carcinogenesis in rats treated with 1,4-dinitrosopiperazine. J Cancer Res Clin Oncol, 108: 186-191, 1984.

26. Fukushima, S., Tsuda, H., Shirai, T., Nakakita, T., Sawaguchi, K., Takahashi, M.: An autopsy case of holoprosencephaly with cyclopia. Nagoya Med J, 29: 1-5, 1984.

27. Ito, N., Ogiso, T., Fukushima, S., Shibata, M., Hagiwara, A.: Carcinogenicity of captafol in B6C3F1 mice. Gann, 75: 853-865, 1984.

28. Tsuda, H., Masui, T., Imaida, K., Fukushima, S., Ito, N.: Promotive effect of primary and secondary bile acids on the induction of γ-glutamyl transpeptidase-positive liver cell foci as a possible endogenous factor for hepatocarcinogenesis in rats. Gann, 75: 871-875, 1984.

29. Tsuda, H., Hasegawa, R., Imaida, K., Masui, T., Moore, MA., Ito, N.: Modifying potential of thirty-one chemicals on the short-term development of γ-glutamyl transpeptidase-positive foci in diethylnitrosamine-initiated rat liver. Gann, 75: 876-883, 1984.

30. Shirai, T., Masuda, A., Hirose, M., Ikawa, E., Ito, N.: Enhancement of N-bis(2- hydroxypropyl)nitrosamine-initiated lung tumor development in rats by bleomycin and N-methyl-N-nitrosourethane. Cancer Lett, 25: 25-31, 1984.

31. Ohtani, M., Fukushima, S., Okamura, T., Sakata, T., Ito, N., Koiso, K., Niijima, T.: Effects of intravesical instillation of antitumor chemotherapeutic agents on bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Cancer, 54: 1525-1529, 1984.

32. Moore, MA., Tsuda, H., Ogiso, T., Mera, Y., Ito, N.: Enhancement of phenotypic instability by α-difluoromethylornithine and butylated hydroxyanisole in rapidly induced rat liver lesions. Cancer Lett, 25: 145-151, 1984.

33. Sakata, T., Shirai, T., Fukushima, S., Hasegawa, R., Ito, N.: Summation and synergism in the promotion of urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine in F344 rats. Gann, 75: 950-956, 1984.

34. Tatematsu, M., Katsuyama, T., Furihata, C., Tsuda, H., Ito, N.: Stable intestinal phenotypic expression of gastric and small intestinal tumor cells induced by N-methyl- N’-nitro-N-nitrosoguanidine or methylnitrosourea in rats. Gann, 75: 957-965, 1984.

35. Yanagi, S., Tsuda, H., Sakamoto, M., Ninomiya, Y., Ito, N.: Evaluation of a histologic classification of mouse liver tumors based on pyruvate kinase isozymes and status of host lipids. J Natl Cancer Inst, 73: 1311-1317, 1984.

36. Fukushima, S., Hagiwara, A., Ogiso, T., Shibata, MA., Kurata, Y., Ito, N.: Spontaneous tumors in F344/DuCrj rats. Nagoya Med J, 29: 163-172, 1984.

37. Ito, N., Fukushima, S., Tsuda, H., Shirai, T., Tatematsu, M., Imaida, K.: Modification of chemical carcinogenesis by antioxidants. In: Fujiki, H. et al (eds.) Cellular Interactions by Environmental Tumor Promoters, pp381-389. Japan Sci Soc Press,Tokyo/VNU Science Press, Utrecht, 1984.

38. Ito, N., Fukushima, S., Shirai, T., Hagiwara, A., Imaida, K.: Drugs, food additives and natural products as promoters in rat urinary bladder carcinogenesis. In: Borzsonyi, K. et al (eds.) Models, Mechanisms and Etiology of Tumour Promotion, IARC Scientific Publications No.56, pp399-407. International Agency for Research on Cancer, Lyon, 1984.