1. Hirose, M., Masuda, A., Kurata, Y., Ikawa, E., Mera, Y., Ito, N.: Histologic and autoradiographic studies on the forestomach of hamsters treated with 2-tert-butylated hydroxyanisole, 3-tert-butylated hydroxyanisole, crude butylated hydroxyanisole, or butylated hydroxytoluene. J Natl Cancer Inst, 76: 143-149, 1986.

2. Fukushima, S., Thamavit, W., Kurata, Y., Ito, N.: Sodium citrate: A promoter of bladder carcinogenesis. Jpn J Cancer Res (Gann), 77: 1-4, 1986.

3. Moore, MA., Thamavit, W., Tsuda, H., Sato, K., Ichihara, A., Ito, N.: Modifying influence of dehydroepiandrosterone on the development of dihydroxy-di-n-propylnitrosamine-initiated lesions in the thyroid, lung and liver of F344 rats. Carcinogenesis, 7: 311-316, 1986.

4. Moore, MA., Tsuda, H., Ito, N.: Dehydrogenase histochemistry of N-ethyl-N-hydroxyethylnitrosamine- induced focal liver lesions in the rat — increase in NADPH-generating capacity. Carcinogenesis, 7: 339-342, 1986.

5. Moore, MA., Nakamura, T., Shirai, T., Ichihara, A., Ito, N.: Immunohistochemical demonstration of increased glucose-6-phosphate dehydrogenase in preneoplastic and neoplastic lesions induced by propylnitrosamines in F344 rats and syrian hamsters. Jpn J Cancer Res (Gann), 77: 131-138, 1986.

6. Moore, MA., Thamavit, W., Tsuda, H., Ito, N.: The influence of subsequent dehydroepiandrosterone, diaminopropane, phenobarbital, butylated hydroxyanisole and butylated hydroxytoluene treatment on the development of preneoplastic and neoplastic lesions in the rat initiated with di-hydroxy-di-N-propyl nitrosamine. Cancer Lett, 30: 153-160, 1986.

7. Hirose, M., Hagiwara, A., Masui, T., Inoue, K., Ito, N.: Combined effects of butylated hydroxyanisole and other antioxidants in induction of forestomach lesions in rats. Cancer Lett, 30: 169-174, 1986.

8. Masui, T., Tsuda, H., Inoue, K., Ogiso, T., Ito, N.: Inhibitory effects of ethoxyquin, 4,4′-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis. Jpn J Cancer Res (Gann), 77: 231-237, 1986.

9. Tatematsu, M., Furihata, C., Mera, Y., Shirai, T., Matsushima, T., Ito, N.: Immunohistochemical demonstration of induction of pyloric glands with low pepsinogen 1 (Pg 1) content in rat stomach by N-methyl-N’-nitro-N-nitrosoguanidine. Jpn J Cancer Res (Gann), 77: 238-243, 1986.

10. Nishio, Y., Kakizoe, T., Ohtani, M., Sato, S., Sugimura, T., Fukushima, S.: L-isoleucine and L-leucine: Tumor promoters of bladder cancer in rats. Science, 231: 843-845, 1986.

11. Ikawa, E., Tsuda, H., Sakata, T., Masui, T., Satoh, K., Sato, K., Ito, N.: Modification potentials of ethyl alcohol and acetaldehyde on development of preneoplastic gultathione S-transferase p-form-positive liver cell foci initiated by diethylnitrosamine in the rat. Cancer Lett, 31: 53-60, 1986.

12. Fukushima, S., Shibata, MA., Shirai, T., Tamano, S., Ito, N.: Roles of urinary sodium ion concentration and pH in promotion by ascorbic acid of urinary bladder carcinogenesis in rats. Cancer Res, 46: 1623-1626, 1986.

13. Ohtani, M., Kakizoe, T., Nishio, Y., Sato, S., Sugimura, T., Fukushima, S., Niijima, T.: Sequential changes of mouse bladder epithelium during induction of invasive carcinomas by N-butyl-N-(4-hydroxybutyl)nitrosamine. Cancer Res, 46: 2001-2004, 1986.

14. Shirai, T., Ikawa, E., Fukushima, S., Masui, T., Ito, N.: Uracil-induced urolithiasis and the development of reversible papillomatosis in the urinary bladder of F344 rats. Cancer Res, 46: 2062-2067, 1986.

15. Sato, A., Yonekura, I., Asakawa, M., Nakahara, H., Nakajima, T., Ohta, S., Shirai, T., Ito, N.: Augmentation of ethanol-induced enhancement of dimethylnitrosamine and diethylnitrosamine metabolism by lowered carbohydrate intake. Jpn J Cancer Res (Gann), 77: 125-130, 1986.

16. Moore, MA., Fukushima, S., Ichihara, A., Sato, K., Ito, N.: Intestinal metaplasia and altered enzyme expression in propylnitrosamine-induced syrian hamster cholangiocellular and gallbladder lesions. Virchows Arch [Cell Pathol], 51: 29-38, 1986.

17. Moore, MA., Thamavit, W., Ichihara, A., Sato, K., Ito, N.: Influence of dehydroepiandrosterone, diaminopropane and butylated hydroxyanisole treatment during the induction phase of rat liver nodular lesions in a short-term system. Carcinogenesis, 7: 1059-1063, 1986.

18. Hirose, M., Masuda, A., Inoue, T., Fukushima, S., Ito, N.: Modification by antioxidants and p,p’-diaminodiphenylmethane of 7,12-dimethylbenz[a]anthracene-induced carcinogenesis of the mammary gland and ear duct in CD rats. Carcinogenesis, 7: 1155-1159, 1986.

19. Hirose, M., Inoue, T., Asamoto, M., Tagawa, Y., Ito, N.: Comparison of the effects of 13 phenolic compounds in induction of proliferative lesions of the forestomach and increase in the labeling indices of the glandular stomach and urinary bladder epithelium of
Syrian golden hamsters. Carcinogenesis, 7: 1285-1289, 1986.

20. Moore, MA., Nakamura, T., Thamavit, W., Ichihara, A., Ito, N.: Immunohistochemically demonstrated suppressed expression of tryptophan oxygenase, a marker for liver differentiation, within putative preneoplastic rat liver lesions. Carcinogenesis, 7: 1393-1396, 1986.

21. Hasegawa, R., Tsuda, H., Shirai, T., Kurata, Y., Masuda, A., Ito, N.: Effect of timing of partial hepatectomy on the induction of preneoplastic liver foci in rats given hepatocarcinogens. Cancer Lett, 32: 15-23, 1986.

22. Hirose, M., Thamavit, W., Asamoto, M., Osawa, T., Ito, N.: Inhibition of glutathione S-transferase P type-positive foci development by linolic acid hydroperoxides and their secondary oxidative products in a rat in vivo mid-term test for liver carcinogens. Toxicol Lett, 32: 51-58, 1986.

23. Tsuda, H., Hacker, HJ., Katayama, H., Masui, T., Ito, N., Bannasch, P.: Correlative histochemical studies on preneoplastic and neoplastic lesions in the kidney of rats treated with nitrosamines. Virchows Arch [Cell Pathol], 51: 385-404, 1986.

24. Tatematsu, M., Furihata, C., Katsuyama, T., Miki, K., Honda, H., Konishi, Y., Ito, N.: Gastric and intestinal phenotypic expressions of human signet ring cell carcinomas revealed by their biochemistry, mucin histochemistry, and ultrastructure. Cancer Res, 46: 4866-4872, 1986.

25. Moore, MA., Nakamura, T., Ito, N.: Immunohistochemically demonstrated glucose-6-phosphate dehydrogenase, γ-glutamyl transpeptidase, ornithine decarboxylase and glutathione S-transferase enzymes: absence of direct correlation with cell proliferation in rat liver putative preneoplastic lesions. Carcinogenesis, 7: 1419-1424, 1986.

26. Masui, T., Asamoto, M., Hirose, M., Fukushima, S., Ito, N.: Disappearance of upward proliferation and persistence of downward basal cell proliferation in rat forestomach papillomas induced by butylated hydroxyanisole. Jpn J Cancer Res (Gann), 77: 854-857, 1986.

27. Hasegawa, R., Fukushima, S., Furukawa, F., Takahashi, M., Ito, N.: Aberrant colonic epithelium in the bladder: Report of a case. J Urol, 136: 901-902, 1986.

28. Ito, N., Hirose, M., Fukushima, S., Tsuda, H., Tatematsu, M., Asamoto, M.: Modifying effects of antioxidants on chemical carcinogenesis. Toxicol Pathol, 14: 315-323, 1986.

29. Kurata, Y., Asamoto, M., Hagiwara, A., Masui, T., Fukushima, S.: Promoting effects of various agents in rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine. Cancer Lett, 32: 125-135, 1986.

30. Shibata, MA., Nakanishi, K., Shibata, M., Masui, T., Miyata, Y., Ito, N.: Promoting effect of sodium chloride in 2-stage urinary bladder carcinogenesis in rats initiated by N-butyl-N- (4-hydroxybutyl)nitrosamine. Urol Res, 14: 201-206, 1986.

31. Ohtani, M., Kakizoe, T., Sato, S., Sugimura, T., Fukushima, S.: Strain differences in mice with invasive bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)nitrosamine. J Cancer Res Clin Oncol, 112: 107-110, 1986.

32. Fukushima, S., Shibata, MA., Kurata, Y., Tamano, S., Masui, T.: Changes in the urine and scanning electron microscopically observed appearance of the rat bladder following treatment with tumor promoters. Jpn J Cancer Res (Gann), 77: 1074-1082, 1986.

33. Masui, T., Hirose, M., Imaida, K., Fukushima, S., Tamano, S., Ito, N.: Sequential changes of the forestomach of F344 rats, Syrian golden hamsters, and B6C3F1 mice treated with butylated hydroxyanisole. Jpn J Cancer Res (Gann), 77: 1083-1090, 1986.

34. Nakamura, TA., Fukushima, S., Ito, N., Takai, Y., Tatemoto, Y., Mori, M.: Histochemical observation of lectin-binding patterns in Paget’s disease. Acta Histochem Cytochem, 19: 451-464, 1986.

35. Tatematsu, M., Mera, Y., Kohda, K., Kawazoe, Y., Ito, N.: Ornithine decarboxylase activity and DNA synthesis in rats after long term treatment with butylated hydroxyanisole, sodium saccharin or phenobarbital. Cancer Lett, 33: 119-124, 1986.

36. Shirai, T., Fukushima, S., Ikawa, E., Tagawa, Y., Ito, N.: Induction of prostate carcinoma in situ at high incidence in F344 rats by a combination of 3,2′-dimethyl-4-aminobiphenyl and ethinyl estradiol. Cancer Res, 46: 6423-6426, 1986.

37. Ito, N., Fukushima, S., Tamano, S., Hirose, M., Hagiwara, A.: Dose response in butylated hydroxyanisole induction of forestomach carcinogenesis in F344 rats. J Natl Cancer Inst, 77: 1261-1265, 1986.

38. Ito, N., Hirose, M., Fukushima, S., Tsuda, H., Shirai, T., Tatematsu, M.: Studies on antioxidants: their carcinogenic and modifying effects on chemical carcinogenesis. Fd Chem Toxicol, 24: 1071-1082, 1986.

39. Hayashi, M., Tsuda, H., Okumura, M., Hirose, M., Ito, N.: Histopathological classification of nephroblastomas in slaughtered swine. J Comp Pathol, 96: 35-46, 1986.

40. Fukushima, S., Shirai, T., Hirose, M., Ito, N.: Significance of L-ascorbic acid and urinary electrolytes in promotion of rat bladder carcinogenesis. In: Hayashi, Y. et al (eds.) Diet, Nutrition and Cancer, pp159-168. Tokyo: Japan Sci Soc Press, Tokyo/VNU Sci Press, Utrecht, 1986.

41. 伊東信行, 白井智之：最近の動物実験モデル. 日本臨牀, 44: 311-317, 1986.

42. 加藤政仁, 吉友和夫, 松下豊顯, 加藤錠一, 林嘉光, 都筑瑞夫, 多代友紀, 伊藤剛, 武内俊彦, 立松正衛：自然退縮した肺癌の1例. 日本胸部疾患学会雑誌, 24: 188-194,1986.

43. 伊東信行, 増井恒夫：肝発癌性物質と動物モデル. 綜合臨牀, 35: 1883-1888, 1986.

44. 鷲見聡, 岸真司, 山田薫, 深津圭子, 坪井隆, 側島久典, 山本崇晴, 一木貴, 鈴木重澄, 杉山成司, 渡辺勇, 戸苅創, 和田義郎, 立松正衛：生下時にすでに皮膚の硬化がみられたSclerema neonatorum の１例. 日本新生児学会雑誌, 22: 652-656, 1986.

45. 奥田宗久：Sodium o-phenylphenate (OPP-Na) ならびに o-phenylphenol (OPP) によるラットおよびマウスの膀胱発癌に関する病理学的研究. 名古屋市立大学医学会雑誌, 37: 157-184, 1986.

46. 伊東信行, 井上忠志, 田川義章, 青木豊彦, 香川雅孝：長期発癌性試験結果の予測を目的とした新しい発癌性検索法 (rapid bioassay for carcinogenesis) の開発とその現況. トキシコロジーフォーラム, 9: 601-611, 1986.

47. 伊東信行, 今井田克己, 小木曽正, 玉野静光, 倉田靖：環境発がん物質とその危険性の評価. 癌と化学療法, 13: 3345-3353, 1986.

48. 鈴木幹三, 岸本明比古, 山本俊幸, 白井智之, 増井恒夫：Minocycline 治療に伴う黒色甲状腺の1例. 内科, 58: 877-879, 1986.

49. 伊東信行：膀胱癌. 発生と進展並びにその修飾. 日本病理学会雑誌, 75: 3-37, 1986.

50. 中園智昭, 下在福, 蟹江太, 加藤作郎, 福島昭治：右室悪性腫瘍に合併した肺梗塞の1例. 名古屋市立病院紀要, 9: 15-21, 1986.

51. 福島昭治, 長谷川良平：発生と進展 -１ ラット. 末舛恵一, 高山昭三, 豊島久真男, 濱岡利之, 佐々木本道 (編) 図説臨床癌シリーズ4. 膀胱癌, pp117-127, 1986.

52. 伊東信行：尿路の腫瘍. 飯島宗一, 石川栄世, 影山圭三, 島峰徹郎, 森亘 (編) 現代病理学大系, Vol.15B, pp293-312: 中山書店, 1986.

1. Moore, MA., Satoh, K., Kitahara, A., Sato, K., Ito, N.: A protein cross-reacting immunohistochemically with rat glutathione s-transferase placental form as a marker for preneoplasia in syrian hamster pancreatic and hepatocarcinogenesis. Jpn J Cancer Res (Gann), 76: 1-4, 1985.

2. Shirai, T., Imaida, K., Ohshima, M., Fukushima, S., Lee, MS., King, CM., Ito, N.: Different responses to phenobarbital promotion in the development of γ-glutamyltranspeptidase-positive foci in the liver of rats initiated with diethylnitrosamine, N-hydroxy-2-acetylaminofluorene and aflatoxin B1. Jpn J Cancer Res (Gann), 76: 16-19, 1985.

3. Shibata, MA., Hagiwara, A., Tamano, S., Fukushima, S., Ito, N.: Subchronic toxicity study of sodium o-phenylphenate in mice. Toxicol Lett, 25: 239-246, 1985.

4. Shirai, T., Takahashi, M., Fukushima, S., Ito, N.: Marked epithelial hyperplasia of the rat glandular stomach induced by long-term administration of iodoacetamide. Acta Pathol Jpn, 35: 35-43, 1985.

5. Furihata, C., Sato, Y., Matsushima, T., Tatematsu, M.: Induction of ornithine decarboxylase and DNA synthesis in rat stomach mucosa by methylglyoxal. Carcinogenesis, 6: 91-94, 1985.

6. Shirai, T., Ikawa, E., Hirose, M., Thamavit, W., Ito, N.: Modification by five antioxidants of 1,2-dimethylhydrazine-initiated colon carcinogenesis in F344 rats. Carcinogenesis, 6: 637-639, 1985.

7. Thamavit, W., Tatematsu, M., Ogiso, T., Mera, Y., Tsuda, H., Ito, N.: Dose-dependent effects of butylated hydroxyanisole, butylated hydroxytoluene and ethoxyquin in induction of foci of rat liver cells containing the placental form of glutathione S-transferase. Cancer Lett, 27: 295-303, 1985.

8. Kurata, Y., Tsuda, H., Tamano, S., Ito, N.: Inhibitory potential of acetaminophen and o-, m-, p-aminophenols for development of γ-glutamyltranspeptidase-positive liver cell foci in rats pretreated with diethylnitrosamine. Cancer Lett, 28: 19-25, 1985.

9. Shirai, T., Hosoda, K., Hirose, K., Hirose, M., Ito, N.: Promoting effects of phenobarbital and 3′-methyl-4-dimethylaminoazobenzene on the appearance of γ-glutamyltranspeptidase positive foci in rat liver pretreated with varying doses of diethylnitrosamine. Cancer Lett, 28: 127-133, 1985.

10. Fukushima, S., Kurata, Y., Ogiso, T., Okuda, M., Miyata, Y., Ito, N.: Pathological analysis of the carcinogenicity of sodium o-phenylphenate and o-phenylphenol. Oncology, 42: 304-311, 1985.

11. Shirai, T., Sakata, T., Fukushima, S., Ikawa, E., Ito, N.: Rat prostate as one of the target organs for 3,2′-dimethyl-4-aminobiphenyl-induced carcinogenesis: Effects of dietary ethinyl estradiol and methyltestosterone. Jpn J Cancer Res (Gann), 76: 803-808, 1985.

12. Ito, N., Fukushima, S., Tsuda, H.: Carcinogenicity and modification of the carcinogenic response by BHA, BHT and other antioxidants. CRC Crit Rev Toxicol, 15: 109-150, 1985.

13. Fukushima, S., Kurata, Y., Tamano, S., Inoue, K., Ito, N.: Promoting effect of trisodium nitrilotriacetate monohydrate on urinary bladder carcinogenesis in rats. Jpn J Cancer Res (Gann), 76: 823-827, 1985.

14. Miyata, Y., Fukushima, S., Hirose, M., Masui, T., Ito, N.: Short-term screening of promoters of bladder carcinogenesis in N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated, unilaterally ureter-ligated rats. Jpn J Cancer Res (Gann), 76: 828-834, 1985.

15. Okamura, T., Fukushima, S., Inoue, K., Ito, N., Ueda, K., Ohtaguro, K.: Sequential studies of rat urinary bladder epithelial lesions induced by ifosfamide (Z4942). J Urol, 134: 778-781, 1985.

16. Tsuda, H., Moore, MA., Asamoto, M., Satoh, K., Tsuchida, S., Sato, K., Ichihara, A., Ito, N.: Comparison of the various forms of glutathione S-transferase with glucose-6-phosphate dehydrogenase and γ-glutamyltranspeptidase as markers of preneoplastic and neoplastic lesions in rat kidney induced by N-ethyl-N-hydroxyethylnitrosamine. Jpn J Cancer Res (Gann), 76: 919-929, 1985.

17. Tatematsu, M., Mera, Y., Ito, N., Satoh, K., Sato, K.: Relative merits of immunohistochemical demonstrations of placental, A, B and C forms of glutathione S-transferase and histochemical demonstration of γ-glutamyl transferase as markers of altered foci during liver carcinogenesis in rats. Carcinogenesis, 6: 1621-1626, 1985.

18. Shirai, T., Masuda, A., Fukushima, S., Hosoda, K., Ito, N.: Effects of sodium L-ascorbate and related compounds on rat stomach carcinogenesis initiated by N-methyl-N’-nitro-N-nitrosoguanidine. Cancer Lett, 29: 283-288, 1985.

19. Kishikawa, H., Mizuno, T., Takagi, I., Yamakawa, Y., Shimozato, T., Honda, K., Tatematsu, M.: Nonfunctioning adrenocortical carcinoma in a young girl. Jpn J Surg, 15: 477-482, 1985.

20. Sumitomo, S., Tatemoto, Y., Fukui, S., Nakamura, T., Fukushima, S., Ito, N., Mori, M.: False positive reaction for carcinoembryonic antigen in paget cells. Virchows Arch [Cell Pathol], 49: 395-399, 1985.

21. Ogiso, T., Tatematsu, M., Tamano, S., Tsuda, H., Ito, N.: Comparative effects of carcinogens on the induction of placental glutathione S-transferase-positive liver nodules in a short-term assay and of hepatocellular carcinomas in a long-term assay. Toxicol Pathol, 13: 257-265, 1985.

22. Fukushima, S., Ito, N.: Papilloma, Forestomach, Rat. In: Jones, TC., Mohr, U., Hunt, RD. (eds.) Digestive System, pp289-292. Springer-Verlag, Berlin, Heidelberg, New York, Tokyo, 1985.

23. Fukushima, S., Ito, N.: Squamous Cell Carcinoma, Forestomach, Rat. In: Jones, TC., Mohr, U., Hunt, RD. (eds.) Digestive System, pp292-295. Springer-Verlag, Berlin, Heidelberg, New York, Tokyo, 1985.

24. Tatematsu, M., Ito, N.: Placental type of glutathione-S-transferase as a new marker for liver carcinogenesis. In: Jones, TC., Konishi, Y., Mohr, U. (eds.) The Liver, Salivary Glands, and Exocrine Pancreas of Laboratory Animals, Vol.28, pp145. Exp Pathol, 1985.

25. Moore, MA., Ito, N.: Comparative aspects of propyl nitrosamine carcinogenesis in Syrian golden hamsters. In: Jones, TC., Konishi, Y., Mohr, U. (eds.) The Liver, Salivary Glands, and Exocrine Pancreas of Laboratory Animals, Vol.28, pp145-146. Exp Pathol, 1985.

26. 下郷卓弥, 杉田倫太郎, 水野力, 高木格, 山川洋右, 岸川博隆, 本多弓小, 村元章, 田中康之, 加藤孝治, 立松正衛：術後DICを合併した潰瘍性大腸炎の１治験例. Medical Postgraduates, 23: 47-51, 1985.

27. 下郷卓弥, 杉田倫太郎, 水野力, 高木格, 山川洋右, 岸川博隆, 本多弓小, 村元章, 田中康之, 加藤孝治, 立松正衛：胆嚢癌を合併した膵管胆管合流異常を伴う先天性胆道拡張症の１例. 外科, 47: 202-204, 1985.

28. 岸川博隆, 水野力, 高木格, 山川洋右, 下郷卓弥, 本多弓小, 立松正衛：小児内分泌非活性副腎皮質癌の１例. 小児外科, 17: 409-413, 1985.

29. 羽田野厚：胃発癌プロモーターに関する実験的研究. 名古屋市立大学医学会雑誌, 36: 81-100, 1985.

30. 津田洋幸, 伊東信行：肝発癌におけるイニシエーションとプロモーション. 消化器科, 2: 471-479, 1985.

31. 中塚孝雄：ハムスター頬嚢の7,12-Dimethylbenz(a)anthraceneの発癌過程における血管変化の機能的および形態的変化の研究. 名古屋市立大学医学会雑誌, 36: 269-284, 1985.

32. 広瀬雅雄, 伊東信行：自然界の発がん物質. 病態生理, 4: 975-982: 1985.

33. 津田洋幸, 増井恒夫, 井上忠志：肝腫瘍病変の三次元的解析. 化学発癌過程から. 最新医学, 41: 67-74, 1985.

34. 増井恒夫：Butylated hydroxyanisole (BHA) の発癌性に関する研究. 名古屋市立大学医学会雑誌, 36: 396-416, 1985.

35. 伊東由紀子, 横山健二郎, 伊藤晃, 増井恒夫：左下眼瞼に発育した眼窩原発悪性リンパ腫の1例. 臨床眼科, 39: 671-674, 1985.

36. 福島昭治, 伊東信行：動物に癌を作る.黒木登志夫 (編) 臨床医のための図説発癌と癌細胞, pp56-63: メジカルビュー社, 1985.

1. Tatematsu, M., Lurie, AG., Rippey, RM., Conran, PB., Arai, M., Fukushima, S., Ito, N.: Possible mechanistic roles of anatomical and functional vascular changes in rat urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine. Cancer Res, 44: 278-284, 1984.

2. Ito, N., Moore, MA., Bannasch, P.: Modification of the development of N-nitrosomorpholine-induced hepatic lesions by 2-acetylaminofluorene, phenobarbital and 4,4′-diaminodiphenylmethane: a sequential histological and histochemical analysis. Carcinogenesis, 5: 335-342, 1984.

3. Furihata, C., Tatematsu, M., Miki, K., Katsuyama, T., Sudo, K., Miyagi, N., Kubota, T., Jin, SS., Kodama, K., Ito, N., Konishi, Y., Suzuki, K., Matsushima, T.: Gastric- and intestinal-type properties of human gastric cancers transplanted into nude mice. Cancer Res, 44: 727-733, 1984.

4. Shirai, T., Arai, M., Sakata, T., Fukushima, S., Ito, N.: Primary carcinomas of urinary bladder diverticula. Acta Pathol Jpn, 34: 417-424, 1984.

5. Tsuda, H., Nakanishi, K., Hatano, A., Okumura, M., Seki, K.: Summational effect of three different hepatopromoters in rats after initiation with diethylnitrosamine. Nagoya Med J, 28: 171-182, 1984.

6. Shirai, T., Ohshima, M., Masuda, A., Tamano, S., Ito, N.: Promotion of 2-(ethylnitrosamino)- ethanol-induced renal carcinogenesis in rats by nephrotoxic compounds: Positive responses with folic acid, basic lead acetate, and N-(3,5-dichlorophenyl)succinimide but not with 2,3-dibromo-1-propanol phosphate. J Natl Cancer Inst, 72: 477-482, 1984.

7. Tsuda, H., Sakata, T., Masui, T., Imaida, K., Ito, N.: Modifying effects of butylated hydroxyanisole, ethoxyquin and acetaminophen on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine. Carcinogenesis, 5: 525-531, 1984.

8. Sato, K., Kitahara, A., Satoh, K., Ishikawa, T., Tatematsu, M., Ito, N.: The placental form of glutathione S-transferase as a new marker protein for preneoplasia in rat chemical hepatocarcinogenesis. Gann, 75: 199-202, 1984.

9. Yanagi, S., Tsuda, H., Sakamoto, M., Fuse, E., Ito, N.: Effects of margarine on hepatocarcinogenesis by N,N’-2,7-fluorenylenebisacetamide in mice. Oncology, 41: 101-105, 1984.

10. Sato, K., Kitahara, A., Yin, Z., Waragai, F., Nishimura, K., Hatayama, I., Ebina, T., Yamazaki, T., Tsuda, H., Ito, N.: Induction by butylated hydroxyanisole of specific molecular forms of glutathione S-transferase and UDP-glucuronyltransferase and inhibition of development of γ-glutamyl transpeptidase-positive foci in rat liver. Carcinogenesis, 5: 473-477, 1984.

11. Shirai, T., Fukushima, S., Ohshima, M., Masuda, A., Ito, N.: Effects of butylated hydroxyanisole, butylated hydroxytoluene, and NaCl on gastric carcinogenesis initiated with N-methyl-N’-nitro-N-nitrosoguanidine in F344 rats. J Natl Cancer Inst, 72: 1189-1198, 1984.

12. Ito, N., Hirose, M., Kurata, Y., Ikawa, E., Mera, Y., Fukushima, S.: Induction of forestomach hyperplasia by crude butylated hydroxyanisole, a mixture of 3-tert and 2-tert isomers, in syrian golden hamsters is due to 3-tert-butylated hydroxyanisole. Gann, 75: 471-474, 1984.

13. Shirai, T., Kurata, Y., Fukushima, S., Ito, N.: Dose-related induction of lung, thyroid and kidney tumors by N-bis(2-hydroxypropyl)nitrosamine given orally to F344 rats. Gann, 75: 502-507, 1984.

14. Fukushima, S., Kurata, Y., Shibata, MA., Ikawa, E., Ito, N.: Promotion by ascorbic acid, sodium erythorbate and ethoxyquin of neoplastic lesions in rats initiated with N-butyl-N-(4-hydroxybutyl) nitrosamine. Cancer Lett, 23: 29-37, 1984.

15. Kitahara, A., Satoh, K., Nishimura, K., Ishikawa, T., Ruike, K., Sato, K., Tsuda, H., Ito, N.: Changes in molecular forms of rat hepatic glutathione S-transferase during chemical hepatocarcinogenesis. Cancer Res, 44: 2698-2703, 1984.

16. Miyata, Y., Fukushima, S., Imaida, K., Ito, N.: Promoting effects of unilateral ureteric ligation on two-stage urinary bladder carcinogenesis in rats. Cancer Lett, 23: 265-272, 1984.

17. Tsuda, H., Sakata, T., Shirai, T., Kurata, Y., Tamano, S., Ito, N.: Modification of N-methyl-N-nitrosourea initiated carcinogenesis in the rat by subsequent treatment with antioxidants, phenobarbital and ethinyl estradiol. Cancer Lett, 24: 19-27, 1984.

18. Ito, N., Shirai, T., Fukushima, S., Hirose, M.: Dose-response study of urinary bladder carcinogenesis in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine. J Cancer Res Clin Oncol, 108: 169-173, 1984.

19. Sato, A., Nakajima, T., Koyama, Y., Shirai, T., Ito, N.: Dietary carbohydrate level as a modifying factor of 3′-methyl-4-dimethylaminoazobenzene liver carcinogenesis in rats. Gann, 75: 665-671, 1984.

20. Tsuda, H., Fukushima, S., Imaida, K., Sakata, T., Ito, N.: Modification of carcinogenesis by antioxidants and other compounds. Acta Pharmacol Toxicol, 55: 125-143, 1984.

21. Tsuda, H., Tamano, S., Imaida, K., Ohshima, M., Kitahori, Y., Ito, N.: Three-dimensional observations by scanning electron microscopy on the blood supply and organization of vasculature during hepatocarcinogenesis in rats. Acta Pathol Jpn, 34: 957-970, 1984.

22. Hagiwara, A., Fukushima, S., Kitaori, M., Shibata, M., Ito, N.: Effects of three sweeteners on rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 75: 763-768, 1984.

23. Imaida, K., Fukushima, S., Shirai, T., Masui, T., Ogiso, T., Ito, N.: Promoting activities of butylated hydroxyanisole, butylated hydroxytoluene and sodium L-ascorbate on forestomach and urinary bladder carcinogenesis initiated with methylnitrosourea in F344 male rats. Gann, 75: 769-775, 1984.

24. Hagiwara, A., Shibata, M., Hirose, M., Fukushima, S., Ito, N.: Long-term toxicity and carcinogenicity study of sodium o-phenylphenate in B6C3F1 mice. Fd Chem Toxicol, 22: 809-814, 1984.

25. Tsuda, H., Takano, T., Shirai, T., Suzuki, M., Baba, S., Ito, N.: Comparative light and scanning electron microscopic observations of nasal cavity carcinogenesis in rats treated with 1,4-dinitrosopiperazine. J Cancer Res Clin Oncol, 108: 186-191, 1984.

26. Fukushima, S., Tsuda, H., Shirai, T., Nakakita, T., Sawaguchi, K., Takahashi, M.: An autopsy case of holoprosencephaly with cyclopia. Nagoya Med J, 29: 1-5, 1984.

27. Ito, N., Ogiso, T., Fukushima, S., Shibata, M., Hagiwara, A.: Carcinogenicity of captafol in B6C3F1 mice. Gann, 75: 853-865, 1984.

28. Tsuda, H., Masui, T., Imaida, K., Fukushima, S., Ito, N.: Promotive effect of primary and secondary bile acids on the induction of γ-glutamyl transpeptidase-positive liver cell foci as a possible endogenous factor for hepatocarcinogenesis in rats. Gann, 75: 871-875, 1984.

29. Tsuda, H., Hasegawa, R., Imaida, K., Masui, T., Moore, MA., Ito, N.: Modifying potential of thirty-one chemicals on the short-term development of γ-glutamyl transpeptidase-positive foci in diethylnitrosamine-initiated rat liver. Gann, 75: 876-883, 1984.

30. Shirai, T., Masuda, A., Hirose, M., Ikawa, E., Ito, N.: Enhancement of N-bis(2- hydroxypropyl)nitrosamine-initiated lung tumor development in rats by bleomycin and N-methyl-N-nitrosourethane. Cancer Lett, 25: 25-31, 1984.

31. Ohtani, M., Fukushima, S., Okamura, T., Sakata, T., Ito, N., Koiso, K., Niijima, T.: Effects of intravesical instillation of antitumor chemotherapeutic agents on bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Cancer, 54: 1525-1529, 1984.

32. Moore, MA., Tsuda, H., Ogiso, T., Mera, Y., Ito, N.: Enhancement of phenotypic instability by α-difluoromethylornithine and butylated hydroxyanisole in rapidly induced rat liver lesions. Cancer Lett, 25: 145-151, 1984.

33. Sakata, T., Shirai, T., Fukushima, S., Hasegawa, R., Ito, N.: Summation and synergism in the promotion of urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine in F344 rats. Gann, 75: 950-956, 1984.

34. Tatematsu, M., Katsuyama, T., Furihata, C., Tsuda, H., Ito, N.: Stable intestinal phenotypic expression of gastric and small intestinal tumor cells induced by N-methyl- N’-nitro-N-nitrosoguanidine or methylnitrosourea in rats. Gann, 75: 957-965, 1984.

35. Yanagi, S., Tsuda, H., Sakamoto, M., Ninomiya, Y., Ito, N.: Evaluation of a histologic classification of mouse liver tumors based on pyruvate kinase isozymes and status of host lipids. J Natl Cancer Inst, 73: 1311-1317, 1984.

36. Fukushima, S., Hagiwara, A., Ogiso, T., Shibata, MA., Kurata, Y., Ito, N.: Spontaneous tumors in F344/DuCrj rats. Nagoya Med J, 29: 163-172, 1984.

37. Ito, N., Fukushima, S., Tsuda, H., Shirai, T., Tatematsu, M., Imaida, K.: Modification of chemical carcinogenesis by antioxidants. In: Fujiki, H. et al (eds.) Cellular Interactions by Environmental Tumor Promoters, pp381-389. Japan Sci Soc Press,Tokyo/VNU Science Press, Utrecht, 1984.

38. Ito, N., Fukushima, S., Shirai, T., Hagiwara, A., Imaida, K.: Drugs, food additives and natural products as promoters in rat urinary bladder carcinogenesis. In: Borzsonyi, K. et al (eds.) Models, Mechanisms and Etiology of Tumour Promotion, IARC Scientific Publications No.56, pp399-407. International Agency for Research on Cancer, Lyon, 1984.

39. 伊東信行, 広瀬雅雄：発癌と動物実験. 実験医学, 2: 274-278, 1984.

40. 伊東信行, 立松正衛：がんの発生因子. 薬局, 35: 487-492, 1984.

41. 鈴木正弓：膀胱発癌プロモーターに関する実験的研究. 名古屋市立大学医学会雑誌, 35: 28-54, 1984.

42. 白井智之, 伊東信行：環境中の発癌修飾因子. 臨床科学, 20: 547-554, 1984.

43. 伊東信行, 福島昭治：ブチルヒドロキシアニソールの発癌性の問題から発癌物質の規制を考える. 代謝, 21: 771-717, 1984.

44. 佐藤章夫, 中島民江,小山裕, 白井智之, 伊東信行：低糖質食による3′-methyl-4- dimethylaminoazobenzene 肝癌の発生促進. 医学のあゆみ, 130: 113-114, 1984.

45. 伊東信行, 福島昭治, 津田洋幸：化学発癌過程のモディフィケーション. 日本医師会雑誌, 92: 575-581, 1984.

46. 伊東信行：発癌メカニズムの解明において環境分析技術に期待するもの. 全国公害研会誌, 9: 51-53, 1984.

47. 水谷晶彦：ラット肝および腎腫瘍発生に及ぼす薬物代謝酵素誘導物質の影響. 名古屋市立大学医学会雑誌, 35: 267-291, 1984.

48. 安藤隆,香川泰生,坂井昇, 山田弘, 今尾幸則, 西村康明, 船越孝, 今井田克己：Ependymoma の頭蓋外転移. Neurol Med Chir, 24: 800-807, 1984.

49. 横井浩, 中間慧, 本田伸行, 島谷裕子, 伊東信行, 日浅義雄, 関浅男, 天野精子, 伊藤健一, 渋谷昇：乳癌の超音波像と病理組織構造の対比 (その１）. 膠原線維と癌細胞の成分のヒストグラム.日生病院医学雑誌, 12: 153-158, 1984.

50. 坂田孝雄：膀胱発癌における修飾要因の複合効果に関する基礎的研究. 名古屋市立大学医学会雑誌, 35: 397-418, 1984.

51. 伊東信行, 白井智之：発癌剤 Chemical carcinogen. 生体の科学, 35: 585-586, 1984.

52. 大野正弘, 杉山尚武, 三沢郁夫, 津田洋幸, 中西敬介：肝癌の脳転移例. 腫瘍内出血で発症した１例. Nuerol Med Chir, 24: 969-973, 1984.

53. 伊東信行, 玉野静光, 井川悦男, 米良幸典：癌の原因としての化学物質. 国際病理アカデミー日本支部 1984年度病理学教育セミナー 39-43, 1984.

54. 伊東信行, 立松正衛：発ガンをめぐって. からだの科学, 120: 52-56, 1984.

55. 伊東信行：発癌物質の臓器特異性. 飯島宗一, 石川栄世, 影山圭三, 島峰徹郎, 森亘 (編) 現代病理学大系, Vol.9B, pp178-189: 中山書店, 1984.

56. 福島昭治：ラットその他の動物の自然発生腫瘍. 飯島宗一, 石川栄世, 影山圭三, 島峰徹郎, 森亘 (編) 現代病理学大系, Vol.9C, pp285-297: 中山書店, 1984.

1. Fukushima, S., Hagiwara, A., Ogiso, T., Shibata, M., Ito, N.: Promoting effects of various chemicals in rat urinary bladder carcinogenesis initiated by N-nitroso-n-butyl-(4-hydroxybutyl)amine. Fd Chem Toxicol, 21: 59-68, 1983.

2. Hotta, K., Yamamoto, Y., Imaida, K., Oshima, M., Fukushima, S., Ito, N.: Membrance potential of rat urinary bladder epithelial cells. Jpn J Physiol, 33: 139-143, 1983.

3. Ito, N., Fukushima, S., Shirai, T., Nakanishi, K., Hasegawa, R., Imaida, K.: Modifying factors in urinary bladder carcinogenesis. Environ Health Perspect, 49: 217-222, 1983.

4. Fukushima, S., Arai, M., Nakanowatari, J., Hibino, T., Okuda, M., Ito, N.: Differences in susceptibility to sodium saccharin among various strains of rats and other animal species. Gann, 74: 8-20, 1983.

5. Shirai, T., Nakanowatari, J., Kurata, Y., Fukushima, S., Ito, N.: Different dose-response relationships in the induction of different types of colonic tumors in Wistar rats by 1,2-dimethylhydrazine. Gann, 74: 21-27, 1983.

6. Takahashi, M., Kokubo, T., Furukawa, F., Kurokawa, Y., Tatematsu, M., Hayashi, Y.: Effect of high salt diet on rat gastric carcinogenesis induced by N-methyl-N’-nitro-N-nitrosoguanidine. Gann, 74: 28-34, 1983.

7. Ito, N., Fukushima, S., Hagiwara, A., Shibata, M., Ogiso, T.: Carcinogenicity of butylated hydroxyanisole in F344 rats. J Natl Cancer Inst, 70: 343-352, 1983.

8. Tatematsu, M., Furihata, C., Katsuyama, T., Hasegawa, R., Nakanowatari, J., Saito, D., Takahashi, M., Matsushima, T., Ito, N.: Independent induction of intestinal metaplasia and gastric cancer in rats treated with N-methyl-N’-nitro-N-nitrosoguanidine. Cancer Res, 43: 1335-1341, 1983.

9. Tatematsu, M., Hasegawa, R., Imaida, K., Tsuda, H., Ito, N.: Survey of various chemicals for initiating and promoting activities in a short-term in vivo system based on generation of hyperplastic liver nodules in rats. Carcinogenesis, 4: 381-386, 1983.

10. Imaida, K., Ishihara, Y., Nishio, O., Nakanishi, K., Ito, N.: Carcinogenicity and toxicity tests on p-phenylenediamine in F344 rats. Toxicol Lett, 16: 259-269, 1983.

11. Tsuda, H., Sakata, T., Tamano, S., Okumura, M., Ito, N.: Sequential observations on the appearance of neoplastic lesions in the liver and kidney after treatment with N- ethyl-N-hydroxyethylnitrosamine followed by partial hepatectomy and unilateral nephrectomy. Carcinogenesis, 4: 523-528, 1983.

12. Imaida, K., Oshima, M., Fukushima, S., Ito, N., Hotta, K.: Membrane potentials of urinary bladder epithelium in F344 rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine or sodium saccharin. Carcinogenesis, 4: 659-661, 1983.

13. Ito, N., Fukushima, S., Shirai, T., Nakanishi, K.: Effects of promoters on N-butyl-N- (4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in the rat. Environ Health Perspect, 50: 61-69, 1983.

14. Ito, N., Tsuda, H., Hasegawa, R., Imaida, K.: Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver. Environ Health Perspect, 50: 131-138, 1983.

15. Imaida, K., Fukushima, S., Shirai, T., Ohtani, M., Nakanishi, K., Ito, N.: Promoting activities of butylated hydroxyanisole and butylated hydroxytoluene on 2-stage urinary bladder carcinogenesis and inhibition of γ-glutamyl transpeptidase-positive foci development in the liver of rats. Carcinogenesis, 4: 895-899, 1983.

16. Tsuda, H., Fukushima, S., Imaida, K., Kurata, Y., Ito, N.: Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea. Cancer Res, 43: 3292-3296, 1983.

17. Ito, N., Fukushima, S., Imaida, K., Sakata, T., Masui, T.: Induction of papilloma in the forestomach of hamsters by butylated hydroxyanisole. Gann, 74: 459-461, 1983.

18. Ito, N., Tsuda, H., Sakata, T., Hasegawa, R., Tamano, S.: Inhibitory effect of butylated hydroxyanisole and ethoxyquin on the induction of neoplastic lesions in rat liver after an initial treatment with N-ethyl-N-hydroxyethylnitrosamine. Gann, 74: 466-468, 1983.

19. Tsuda, H., Miyata, Y., Hatano, A., Inui, M., Ito, N.: Effects of dietary lithocholic and deoxycholic acids on rat liver. Nagoya Med J, 28: 65-70, 1983.

20. Fukushima, S., Imaida, K., Sakata, T., Okamura, T., Shibata, MA., Ito, N.: Promoting effects of sodium L-ascorbate on two-stage urinary bladder carcinogenesis in rats. Cancer Res., 43: 4454-4457, 1983.

21. Hayashi, M., Tsuda, H., Ito, N.: Histopathological classification of spontaneous hyperplastic liver nodules in slaughtered swine. J Comp Pathol, 93: 603-612, 1983.

22. Tamano, S., Tsuda, H., Fukushima, S., Masui, T., Hosoda, K., Ito, N.: Dose and sex dependent effects of 2-acetylaminofluorene, 3′-methyl-4-dimethylaminoazobenzene and DL-ethionine in induction of γ-glutamyl transpeptidase-positive liver cell foci in rats. Cancer Lett, 20: 313-321, 1983.

23. Fukushima, S., Kurata, Y., Shibata, MA., Ikawa, E., Ito, N.: Promoting effect of sodium o-phenylphenate and o-phenylphenol on two-stage urinary bladder carcinogenesis in rats. Gann, 74: 625-632, 1983.

24. Hirose, M., Fukushima, S., Sakata, T., Inui, M., Ito, N.: Effect of quercetin on two-stage carcinogenesis of the rat urinary bladder. Cancer Lett, 21: 23-27, 1983.

25. Lurie, AG., Tatematsu, M., Nakatsuka, T., Rippey, RM., Ito, N.: Anatomical and functional vascular changes in hamster cheek pouch during carcinogenesis induced by 7,12-dimethylbenz(a)anthracene. Cancer Res, 43: 5986-5994, 1983.

26. Hagiwara, A., Shibata, M., Kurata, Y., Seki, K., Fukushima, S., Ito, N.: Long-term toxicity and carcinogenicity test of ammonia-process caramel colouring given to B6C3F1 mice in the drinking-water. Fd Chem Toxicol, 21: 701-706, 1983.

27. Ohtani, M., Fukushima, S., Ito, N., Koiso, K., Niijima, T.: Effects of intravesical instillation of antitumor drugs on the induction of preneoplastic bladder lesions in rats. Cancer Chemother Pharmacol, 11 (Suppl): S64-S66, 1983.

28. Tsuda, H.: Goiter, adenoma, and carcinoma of the thyroid induced by amitrole and ethylenethiourea, rat. In: Jones, TC., Moher, U., Hunt, RD.(eds.) Endocrine System, pp204-211. Springer-Verlag, Berlin, Heidelberg, New York, Tokyo, 1983.

29. Sato, K., Kitahara, A., Yin, Z., Ebina, T., Satoh, K., Tsuda, H., Ito, N., Dempo, K.: Molecular forms of glutathione S-transferase and UDP-glucuronyltransferase as hepatic preneoplastic marker enzymes. In: Alpert, E., Hirai, H. (eds.) Annals of the New York Academy of Sciences, Vol.417, pp213-223. ANN N.Y. Acad Sci, New York, 1983.

30. 伊東信行：膀胱腫瘍の組織分類. 臨床泌尿器科, 37: 101-107, 1983.

31. 福島昭治：プロモーターの臓器特異性. Oncologia, 6: 173-174, 1983.

32. 岸川博隆, 藤井康, 林聰一, 上田常義, 本多弓小, 小林端, 津田洋幸：Halothane によるmassive hepatic necrosisの1例. 小児外科, 15: 1067-1071, 1983.

33. 福島昭治：環境要因と膀胱癌. 医学のあゆみ, 127: 16-17, 1983.

34. 伊東信行, 今井田克己, 増井恒夫：酸化防止剤の発癌性をめぐる最近の知見. Oncologia, 6: 132-144, 1983.

1. Tatematsu, M., Katsuyama, T., Nakanowatari, J., Hasegawa, R., Imaida, K., Fukushima, S., Ito, N.: Region-specific patterns of mucin reaction demonstrated by paradoxical concanavalin A-staining in normal colonic epithelium and in colorectal cancers induced in rats by 1,2-dimethylhydrazine. Gann, 73: 77-84, 1982.

2. Hasegawa, R., Tsuda, H., Ogiso, T., Ohshima, M., Ito, N.: Initiating activities of pyrolysis products of L-lysine and soybean globulin assessed in terms of the induction of γ-glutamyl transpeptidase-positive foci in rat liver. Gann, 73: 158-159, 1982.

3. Fukushima, S., Murasaki, G., Hirose, M., Nakanishi, K., Hasegawa, R., Ito, N.: Histopathological analysis of preneoplastic changes during N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis in rats. Acta Pathol Jpn, 32: 243-250, 1982.

4. Nakanishi, K., Kurata, Y., Ohshima, M., Fukushima, S., Ito, N.: Carcinogenicity of phenacetin: long-term feeding study in B6C3F1 mice. Int J Cancer, 29: 439-444, 1982.

5. Nakanishi, K., Fukushima, S., Hagiwara, A., Tamano, S., Ito, N.: Organ-specific promoting effects of phenobarbital sodium and sodium saccharin in the induction of liver and urinary bladder tumors in male F344 rats. J Natl Cancer Inst, 68: 497-500, 1982.

6. Yin, Z., Sato, K., Tsuda, H., Ito, N.: Changes in activities of uridine diphosphate- glucuronyltransferases during chemical hepatocarcinogenesis. Gann, 73: 239-248, 1982.

7. Hasegawa, R., Tatematsu, M., Tsuda, H., Shirai, T., Hagiwara, A., Ito, N.: Induction of hyperplastic liver nodules in hepatectomized rats treated with 3′-methyl-4-dimethylaminoazobenzene, benzo[a]pyrene or phenobarbital before or after exposure to N-2-fluorenylacetamide. Gann, 73: 264-269, 1982.

8. Ito, N., Hagiwara, A., Shibata, M., Ogiso, T., Fukushima, S.: Induction of squamous cell carcinoma in the forestomach of F344 rats treated with butylated hydroxyanisole. Gann, 73: 332-334, 1982.

9. Hasegawa, R., Tatematsu, M., Imaida, K., Murasaki, G., Ito, N., Watanabe, I., Nakazato, M.: Neuroblastoma in situ. Acta Pathol Jpn, 32: 537-546, 1982.

10. Hirose, M., Takahashi, M., Fukushima, S., Shibata, M., Ito, N.: Chronic effects of 1,3-di(4-sulfamoylphenyl)triazene on male ICR mice. Nagoya Med J, 26: 173-177, 1982.

11. Cameron, RG., Imaida, K., Tsuda, H., Ito, N.: Promotive effects of steroids and bile acids on hepatocarcinogenesis initiated by diethylnitrosamine. Cancer Res, 42: 2426-2428, 1982.

12. Imaida, K., Hirose, M., Ogisa, T., Kurata, Y., Ito, N.: Quantitative analysis of initiating and promoting activities of five mycotoxins in liver carcinogenesis in rats. Cancer Lett, 16: 137-143, 1982.

13. Fukushima, S., Hirose, M., Okuda, M., Nakanowatari, J., Hatano, A., Ito, N.: Effect of partial cystectomy on the induction of pre-neoplastic lesions in rat bladder initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine followed by bladder carcinogens and promoters. Urol Res, 10: 115-118, 1982.

14. Takano, T., Shirai, T., Ogiso, T., Tsuda, H., Baba, S., Ito, N.: Sequential changes in tumor development induced by 1,4-dinitrosopiperazine in the nasal cavity of F344 rats. Cancer Res, 42: 4236-4240, 1982.

15. Hasegawa, R., Tsuda, H., Nakanishi, K., Tatematsu, M., Ito, N.: Route-dependent, organ-specific effects of carcinogens on induction of hyperplastic liver nodules in rats. Toxicol Lett, 14: 229-235, 1982.

16. Shirai, T., Hagiwara, A., Kurata, Y., Shibata, M., Fukushima, S., Ito, N.: Lack of carcinogenicity of butylated hydroxytoluene on long-term administraiton to B6C3F1 mice. Fd Chem Toxicol, 20: 861-865, 1982.

17. Ogiso, T., Arai, Y., Fukushima, S., Nishizuka, Y., Ito, N.: Enhancing effect of diethylstilbestrol on urinary bladder carcinogenesis in neonatally castrated male rats. Gann, 73: 862-869, 1982.

18. Shirai, T., Imaida, K., Fukushima, S., Hasegawa, R., Tatematsu, M., Ito, N.: Effects of NaCl, Tween 60 and a low dose of N-ethyl-N’-nitro-N-nitrosoguanidine on gastric carcinogenesis of rat given a single dose of N-methyl-N’-nitro-N-nitrosoguanidine. Carcinogenesis, 3: 1419-1422, 1982.

19. Tsuda, H., Hagiwara, A., Shibata, M., Ohshima, M., Ito, N.：Carcinogenic effect of carbazole in the liver of (C57BL/6N x C3H/HeN)F1 mice. J Natl Cancer Inst, 69: 1383-1389, 1982.

20. Yanagi, S., Sakamoto, M., Tsuda, H., Tatematsu, M., Ito, N., Yamamoto, N., Furuyama, S.: Effect of safflower oil and safflower margarine on hepatic tumorigenesis by N,N’-2,7-fluorenylenebisacetamide. J Nara Med Assoc, 33: 545-548, 1982.

21. Hasegawa, R., Imaida, K., Fukushima, S., Tsuda, H., Ito, N., Masuko, K.: Effect of hemodialysis on amyloid deposition (18 Autopsy Cases). Nagoya Med J, 27: 277-286, 1982.

22. Ito, N., Tsuda, H., Hasegawa, R., Imaida, K.: Sequential observation of pathomorphologic alterations in preneoplastic lesions during the promoting stage of hepatocarcinogenesis and the development of short-term test system for hepatopromoters and hepatocarcinogens. Toxicol Pathol, 10: 37-49, 1982.

23. Ito, N., Tatematsu, M., Nakanishi, K., Tsuda, H.: Analysis of the effect of promoting agents on liver and urinary bladder carcinogenesis in rats. In: Hecker, E., Fusenig, NE., Kunz, W., Marks, F., Thielmann, HW.(eds.) Carcinogenesis. A Comprehensive Survey, Vol.7, pp133-137. Raven Press, New York, 1982.

24. Ito, N., Fukushima, S., Tsuda, H., Shirai, T., Arai, M.: Induction of preneoplastic and neoplastic lesions in rats treated N-nitroso compounds. In: Bartsch, H., O’Neill, IK., Castegnaro, M., Okada, M. (eds.) N-nitroso-compounds: Occurrence and Biological Effects, IARC Scientific Publication Vol.41, pp597-601. International Agency for Research on Cancer, Lyon, 1982.

25. Ito, N., Nakanishi, K., Fukushima, S., Tsuda, H., Shirai, T.: Promoting and inhibiting factors on liver and urinary bladder carcinogenesis in rats. In: Pani, P., Feo, F., Columbano, A. (eds.) Recent Trends in Chemical Carcinogenesis, Vol.1, pp199-213. ESA, Cagliari, 1982.

26. 伊東信行, 荒井昌之：泌尿器科系疾患の微細構造の見方 (6). 膀胱腫瘍. 臨床泌尿器科, 36: 525-533, 1982.

27. 福島昭治：光学顕微鏡の画像処理. 映像情報, 14: 517-522, 1982.

28. 萩原昭裕：膀胱腫瘍発生に及ぼすAromatic Retinoidの影響についての実験的研究. 名古屋市立大学医学会雑誌, 33: 1-16, 1982.

29. 伊東信行, 福島昭治：膀胱癌組織分類の実際. 臨床病理, 30: 707-714, 1982.

30. 福島昭治：プロモーターの臓器特異性とその要因. 発癌プロモーターの臓器特異性. 最新医学, 37: 1720-1724, 1982.

31. 津田洋幸：発癌における各種プロモーターとその特性. 化学発癌におけるプロモーターの用量相関. 最新医学, 37: 1756-1761, 1982.

32. 今井田克己：前癌病変を指標とした肝発癌のイニシエーターおよびプロモーターに関する実験的研究. 名古屋市立大学医学会雑誌, 33: 453-472, 1982.

33. 佐藤清美, 北原明夫, 尹宗柱, 西村幸也, 蝦名鉄徳, 津田洋幸, 伊東信行：プロモーターの作用機序. 肝発癌のプロモーション過程における酵素偏倚, 特に解熱系酵素を中心に. 最新医学, 37: 1668-1672, 1982.

34. 伊東信行：癌の原因と予防をめぐる最近の知見. 日生病院医学雑誌, 10: 1-8, 1982.

35. 白井智之, 伊東信行：化学物質による腎腫瘍の発生. 変異原と毒性, 5: 317-325, 1982.

36. 鳥井義夫, 杉浦孝彦, 五十里明, 鈴木雅之, 橋上裕, 松原充隆, 市村貴美子, 青木一, 森下宗彦, 高田勝利, 山本正彦, 福島昭治, 今井田克己, 荒井昌之：Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) およびEaton-Lambert症候群を呈した肺小細胞癌の一例. 肺癌, 22: 575-583, 1982.
 

1. Cameron, R., Imaida, K., Ito, N.: Promotive effects of ethinyl estradiol in hepatocarcinogenesis initiated by diethylnitrosamine in male rats. Gann, 72: 339-340, 1981.

2. Hirose, M., Shibata, M., Hagiwara, A., Imaida, K., Ito, N.: Chronic toxicity of butylated hydroxytoluene in Wistar rats. Fd Cosmet Toxicol, 19: 147-151, 1981.

3. Tatematsu, M., Imaida, K., Ito, N., Togari, H., Suzuki, Y., Ogiu, T.: Sandhoff disease. Acta Pathol Jpn, 31: 503-512, 1981.

4. Tatematsu, M., Imaida, K., Fukushima, S., Arai, M., Mizutani, M., Ito, N.: Cytopathological effect of partial cystectomy of rats. Acta Pathol Jpn, 31: 535-543, 1981.

5. Ito, N., Hirose, M., Shirai, T., Tsuda, H., Nakanishi, K., Fukushima, S.: Lesions of the urinary bladder epithelium in 125 autopsy cases. Acta Pathol Jpn, 31: 545-557, 1981.

6. Cameron, R., Imaida, K., Ito, N.: Promotive effects of deoxycholic acid on hepatocarcinogenesis initiated by diethylnitrosamine in male rats. Gann, 72: 635-636, 1981.

7. Takahashi, M., Shirai, T., Fukushima, S., Ito, N., Kokubo, T., Furukawa, F., Kurata, Y.: Ulcer formation and associated tumor production in multiple sites within the stomach and duodenum of rats treated with N-methyl-N’-nitro-N-nitrosoguanidine. J Natl Cancer Inst, 67: 473-479, 1981.

8. Hirose, M., Imaida, K., Ito, H., Hayashi, M., Ishihara, Y., Ito, N.: Effects of chloroform and dimethylnitrosamine on renal carcinogenesis in unilaterally nephrectomized rats fed formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide. Carcinogenesis, 2: 703-708, 1981.

9. Tamano, S., Tsuda, H., Tatematsu, M., Hasegawa, R., Imaida, K., Ito, N.: Induction of γ-glutamyl transpeptidase positive foci in rat liver by pyrolysis products of amino acids. Gann, 72: 747-753, 1981.

10. Fukushima, S., Ishihara, Y., Nishio, O., Ogiso, T., Shirai, T., Ito, N.: Carcinogenicities of quinoline derivatives in F344 rats. Cancer Lett, 14: 115-123, 1981.

11. Suganuma, T., Katsuyama, T., Tsukahara, M., Tatematsu, M., Sakakura, Y., Murata, F.: Comparative histochemical study of alimentary tracts with special reference to the mucous neck cells of the stomach. Am J Anatomy, 161: 219-238, 1981.

12. Fukushima, S., Hirose, M., Hagiwara, A., Hasegawa, R., Ito, N.: Inhibitory effect of 4,4’-diaminodiphenylmethane on liver, kidney and bladder carcinogenesis in rats ingesting N-ethyl-N-hydroxyethylnitrosamine or N-butyl-N-(4-hydroxybutyl)nitrosamine. Carcinogenesis, 2: 1033-1037, 1981.

13. Sato, K., Hatayama, I., Hoshino, K., Imai, F., Tsuchida, S., Sato, T., Nishimura, K., Tatematsu, M., Ito, N.: Enzyme deviation patterns in primary rat hepatomas induced by sequential administration of two chemically different carcinogens. Cancer Res, 41: 4147-4153, 1981.

14. Imaida, K., Shirai, T., Tatematsu, M., Takano, T., Ito, N.: Dose responses of five hepatocarcinogens for the initiation of rat hepatocarcinogenesis. Cancer Lett, 14: 279-283, 1981.

15. Hirose, M., Shirai, T., Tsuda, H., Fukushima, S., Ogiso, T., Ito, N.: Effect of phenobarbital, polychlorinated biphenyl and sodium saccharin on hepatic and renal carcinogenesis in unilaterally nephrectomized rats given N-ethyl-N-hydroxyethylnitrosamine orally. Carcinogenesis, 2: 1299-1302, 1981.

16. Ito, N.: In vivo carcinogenesis of 4-nitroquinoline 1-oxide and related compounds. In: Sugimura, T. (ed.) Carcinogenesis, Vol. 6, pp117-153. Raven Press, New York, 1981.

17. 福島昭治, 伊東信行：発癌物質による初期病変. 総合臨牀, 30: 215-218, 1981.

18. 福島昭治, 伊東信行：発がんプロモーターの用量効果と臓器特異性. 変異原と毒性, 13: 20-30, 1981.

19. 小林道生, 犬飼和久, 側島久典, 神谷賢二, 山川毅, 長谷川良平, 宮田幸忠：Pneumocystis carinii 肺炎で縦隔気腫を合併した乳児白血病の１剖検例. 肺硝子膜の出現をみた光顕所見を中心に. 小児科臨床, 34: 28-34, 1981.

20. 伊東信行：発ガン機序. からだの科学 16-20, 1981.

21. 吉村卓：4,4′-diaminodiphenylmethane (DDPM) のラット肝に対する影響と1,2-dimethylhydrazine (DMH) による大腸癌発生への効果に関する研究. 名古屋市立大学医学会雑誌, 32: 270-283, 1981.

22. 長谷川良平：Diethylnitrosamine 投与ラットの肝過形成結節発生に及ぼす諸要因. 名古屋市立大学医学会雑誌, 32: 310-326, 1981.

23. 高野剛：鼻腔癌モデルに関する研究. 1,4-dinitrosopiperazine によるラット鼻腔癌発生について. 名古屋市立大学医学会雑誌, 32: 348-366, 1981.

24. 津田洋幸, 伊東信行：前癌状態としての実験的肝過形成結節. 臨床科学, 17: 1326-1332, 1981.

25. 奥田宗久, 中野渡純一, 福島昭治：BBN によるラット膀胱の初期変化に関する形態学的研究. 社会保険医学雑誌, 21: 30-34, 1981.

1. Tada, M., Takahashi, K., Kawazoe, Y., Ito, N.: Binding of quinoline to nucleic acid in a subcellular microsomal system. Chem Biol Interact, 29: 257-266, 1980.

2. Miyata, Y., Hagiwara, A., Nakatsuka, T., Murasaki, G., Arai, M., Ito, N.: Effects of caffeine and saccharin on DNA in the bladder epithelium of rats treated with N-butyl-N-(3-carboxypropyl)nitrosamine. Chem Biol Interact, 29: 291-302, 1980.

3. Hayashi, M., Ishihara, Y., Nishio, O., Tatematsu, M., Makino, M., Asai, T.: Histopathological observations of spontaneous tumors in slaughtered-animals (73 cases). Nagoya Med J, 24: 163-176, 1980.

4. Arai, M., Ito, H., Nakanishi, K., Hasegawa, R., Yoshimura, T., Murasaki, G., Ito, N.: Ultrastructural study of changes of the basement membrane and capillaries of the urinary bladder in rats induced by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Nagoya Med J, 24: 177-187, 1980.

5. Tatematsu, M., Saito, D., Furihata, C., Miyata, Y., Nakatsuka, T., Ito, N., Sugimura, T.: Initial DNA damage and heritable permanent change in pepsinogen isoenzyme pattern in the pyloric mucosae of rats after short-term administration of N-methyl-N’-nitro-N-nitrosoguanidine. J Natl Cancer Inst, 64: 775-781, 1980.

6. Tatematsu, M., Katsuyama, T., Fukushima, S., Takahashi, M., Shirai, T., Ito, N., Nasu, T.: Mucin histochemistry by paradoxical concanavalin A staining in experimental gastric cancers induced in Wistar rats by N-methyl-N’-nitro-N-nitrosoguanidine or 4-nitroquinoline 1-oxide. J Natl Cancer Inst, 64: 835-843, 1980.

7. Murasaki, G., Miyata, Y., Babaya, K., Arai, M., Fukushima, S., Ito, N.: Inhibitory effect of an aromatic retinoic acid analog on urinary bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 71: 333-340, 1980.

8. Miyata, Y., Nakatsuka, T., Arai, M., Murasaki, G., Nakanishi, K., Ito, N.: Inhibition by an aromatic retinoid of DNA damage induced by the bladder carcinogen N-butyl-N-(3-carboxypropyl)nitrosamine. Gann, 71: 341-348, 1980.

9. Ito, N., Tatematsu, M., Imaida, K., Hasegawa, R., Murasaki, G.: Effects of various promoters on the induction of hyperplastic nodules in rat liver. Gann, 71: 415-416, 1980.

10. Hagiwara, A., Arai, M., Hirose, M., Nakanowatari, J., Tsuda, H., Ito, N.: Chronic effects of norharman in rats treated with aniline. Toxicol Lett, 6: 71-75, 1980.

11. Cohen, SM., Tatematsu, M., Shinohara, Y., Nakanishi, K., Ito, N.: Neovascularization in rats during urinary bladder carcinogenesis induced by N-[4-(5-nitro-2-furyl)thiazolyl]formamide. J Natl Cancer Inst, 65: 145-148, 1980.

12. Nakanishi, K., Hirose, M., Ogiso, T., Hasegawa, R., Arai, M., Ito, N.: Effect of sodium saccharin and caffeine on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 71: 490-500, 1980.

13. Takano, T., Tatematsu, M., Hasegawa, R., Imaida, K., Ito, N.: Dose-response relationship for the promoting effect of phenobarbital on the induction of liver hyperplastic nodules in rats exposed to 2-fluorenylacetamide and carbon tetrachloride. Gann, 71: 580-581, 1980.

14. Hirose, M., Murasaki, G., Imaida, K., Fukushima, S., Ito, N.: Effect of cyclophosphamide on rat urinary bladder epithelium treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 71: 729-732, 1980.

15. Hirose, M., Fukushima, S., Shibata, M., Ito, N.: Chronic effects of oral ethylenecyanohydrin on male rats and mice. Nagoya Med J, 25: 1-5, 1980.

16. Nakanishi, K., Hagiwara, A., Shibata, M., Imaida, K., Tatematsu, M., Ito, N.: Dose response of saccharin in induction of urinary bladder hyperplasias in Fischer 344 rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine. J Natl Cancer Inst, 65: 1005-1010, 1980.

17. Takahashi, M., Arai, M., Kokubo, T., Furukawa, F., Kurata, Y., Ito, N.: An ultrastructural study of precancerous and cancerous lesions of the pancreas in Syrian golden hamsters induced by N-nitrosobis(2-oxopropyl)amine. Gann, 71: 825-831, 1980.

18. Ito, N., Tatematsu, M., Nakanishi, K., Hasegawa, R., Takano, T., Imaida, K., Ogiso, T.: The effects of various chemicals on the development of hyperplastic liver nodules in hepatectomized rats treated with N-nitrosodiethylamine or N-2-fluorenylacetamide. Gann, 71: 832-842, 1980.

19. Tatematsu, M., Takano, T., Hasegawa, R., Imaida, K., Nakanowatari, J., Ito, N.: A sequential quantitative study of the reversibility or irreversibility of liver hyperplastic nodules in rats exposed to hepatocarcinogens. Gann, 71: 843-855, 1980.

20. Ito, N., Nakanishi, K., Hagiwara, A., Shibata, M., Fukushima, S.: Induction of hyperplasic liver nodules by phenobarbital in rats initiated with N-butyl-N-(4- hydroxybutyl)nitrosamine. Gann, 71: 918-919, 1980.

21. 新居均：膵臓癌発生に関する実験的研究. 名古屋市立大学医学会雑誌, 30: 365-386, 1980.

22. 伊東信行：ラット肝癌の発生と前癌病変. 癌と化学療法, 7: 55-63, 1980.

23. 立松正衛：プロモーターの閾値と臓器特異性について. 癌と化学療法, 7: 180-190, 1980.

24. 宮田幸忠, 村崎元五, 長谷川良平, 広瀬雅雄, 高橋道人, 伊東信行：悪性黒色腫の剖検６例. 癌の臨床, 26:
287-291, 1980.

25. 伊東信行, 津田洋幸：発がんにおけるイニシエーションとプロモーション. 変異原と毒性, 11: 4-12, 1980.

26. 長谷川良平, 宮田幸忠, 広瀬雅雄, 斉藤一史, 本多英邦, 平野真：慢性骨髄性白血病に合併した胃アニサキス症の１剖検例. 癌の臨床, 26: 1263-1266, 1980.

27. 広瀬雅雄, 村崎元五, 伊東信行：ホジキン病. 日本臨牀, 38: 3836-3839, 1980.

28. 広瀬雅雄, 今井田克己, 伊東信行, 荻生俊昭, 八木英二, 前田甲子郎：日本住血吸虫症にみられる三重複癌の１剖検例. 癌の臨床, 26: 1692-1697, 1980.

29. 中西啓介：膀胱腫瘍発生に及ぼすSodium Saccharinの影響についての実験的研究. 名古屋市立大学医学会雑誌, 31: 310-326, 1980.

30. 御供泰治, 樋上昌男, 仁田正和, 吉川公章, 平野真, 細井惇, 川村秀和, 山本正彦, 立松正衛, 伊東信行：摘脾後の急性転化に際し多彩な症状を呈した慢性骨髄性白血病の１例. 臨床血液, 21: 1904-1908, 1980.

1. Tatematsu, M., Murasaki, G., Nakanishi, K., Miyata, Y., Shinohara, Y., Ito, N.: Sequential quantitative studies on hyperplastic nodules in the liver of rats treated with carcinogenic chemicals. Gann, 70: 125-130, 1979.

2. Murasaki, G., Miyata, Y., Shirai, T., Arai, M., Kawachi, T., Ito, N.: Effects of the co-mutagen norharman in rats. Toxicol Lett, 3: 157-161, 1979.

3. Fukushima, S., Shibata, M., Hibino, T., Yoshimura, T., Hirose, M., Ito, N.: Intrahepatic bile duct proliferation induced by 4,4’-diaminodiphenylmethane in rats. Toxicol Appl Pharmacol, 48: 145-155, 1979.

4. Shinohara, Y., Hasegawa, R., Ito, N., Kanayama, M., Kato, T., Wada, Y.: Tyrosinemia. Acta Pathol Jpn, 29: 615-622, 1979.

5. Arai, M., Aoki, Y., Nakanishi, K., Miyata, Y., Mori, T., Ito, N.: Long-term experiment of maximal non-carcinogenic dose of dimethylnitrosamine for carcinogenesis in rats. Gann, 70: 549-558, 1979.

6. Hirose, M., Maekawa, A., Kamiya, S., Odashima, S.: Carcinogenic effect of N-ethyl- and N-amyl-N-nitrosourethans on female Donryu rats. Gann, 70: 653-662, 1979.

7. Lurie, AG., Rippey, RM., Conran, PB., Tatematsu, M., Ito, N.: A technique for multiparametric analysis of hemodynamic changes in rat urinary bladder during carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 70: 717-718, 1979.

8. Tatematsu, M., Nakatsuka, T., Lurie, AG., Rippey, RM., Suzuki, M., Ito, N.: Neovascularization during hamster cheek pouch carcinogenesis induced by 7,12-dimethylbenz[a]anthracene. Gann, 70: 719-720, 1979.

9. Tsuchida, S., Hoshino, K., Sato, T., Ito, N., Sato, K.: Purification of γ-glutamyltranferases from rat hepatomas and hyperplastic hepatic nodules, and comparison with the enzyme from rat kidney. Cancer Res, 39: 4200-4205, 1979.

10. Tatematsu, M., Nakanishi, K., Murasaki, G., Miyata, Y., Hirose, M., Ito, N.: Enhancing effect of inducers of liver microsomal enzymes on induction of hyperplastic liver nodules by N-2-fluorenylacetamide in rats. J Natl Cancer Inst, 63: 1411-1416, 1979.

11. Ito, N., Takahashi, M., Fukushima, S., Shirai, T., Tatematsu, M.: Factors which modify induction of experimental glandular gastric cancer in rats and mice. In: Pfeiffer, CJ.(ed.) Experimental Gastric Cancer. Etiology and Pathogenesis, pp277-301. Gerhard Witzstrock Publising House, Inc., New York, 1979.

12. Imai, F., Takaya, S., Hatayama, I., Sato, T., Ito, N., Sato, K.: Rat hyperplastic hepatic nodules and primary hepatomas retaining abnormally high pyruvate kinase L type activity. In: Colombo, JP., Frei, J., Greengard, O., Knox, WE. (eds.) Enzyme, Vol.24, pp313-321. S. Karger, Basel, 1979.

13. 村崎元五, 立松正衛, 広瀬雅雄, 伊東信行, 川原弘久, 山崎親雄, 八田正弘, 増子美奈子, 増子和郎, 大倉誉暢：人工透析患者の１３剖検例についての観察. 日本腎臓学会誌, 21: 91-100, 1979.

14. 日浅義雄, 大嶋正人, 榊寿右, 関浅男, 大森知美, 空地民樹, 林勝, 仲原正明, 横井浩, 伊東信行：急性出血性膵炎の１剖検例. 日生病院医学雑誌, 7: 277-283, 1979.

15. 篠原良孝, 広瀬雅雄, 伊東信行, 新美明達, 大田黒和生：幼児の肺過誤腫を伴った原発性膀胱横紋筋肉腫の１剖検例. 癌の臨床, 25: 354-357, 1979.

16. 伊東信行, 広瀬雅雄：前癌病変.太田邦夫, 山本正, 杉村隆, 菅野晴夫 (編) 環境と発癌, pp245-259, 南江堂, 1979.

17. 伊東信行：病理学からみて発癌の機作を考える. マイコトキシン, 9: 17-19, 1979.

18. 伊東信行, 荒井昌之：膀胱癌. 動物.太田邦夫, 山本正, 杉村隆, 菅野晴夫 (編) 癌の科学４：ヒト癌と動物モデル, pp387-402: 南江堂, 1979.

1. Tatematsu, M., Takahashi, M., Tsuda, H., Ogiso, T., Ito, N.: The administration of reserpine to rats for 75 weeks. Toxicol Lett, 1: 201-205, 1978.

2. Ito, N., Tatematsu, M., Hirose, M., Nakanishi, K., Murasaki, G.: Enhancing effect of chemicals on production of hyperplastic liver nodules induced by N-2-fluorenylacetamide in hepatectomized rats. Gann, 69: 143-144, 1978.

3. Shirai, T., Cohen, SM., Fukushima, S., Hananouchi, M., Ito, N.: Reversible papillary hyperplasia of the rat urinary bladder. Am J Pathol, 91: 33-48, 1978.

4. Hiasa, Y., Ito, N., Ohshima, M., Ohmori, T., Seki, A., Tatsumi, T., Yokoi, H., Iwata, C., Murata, Y., Ito, N.: Ultrastructure of an anaplastic giant-cell carcinoma found 8 years after operation of a papillary carcinoma of the thyroid. Acta Pathol Jpn, 28: 637-644, 1978.

5. Takahashi, M., Shirai, T., Fukushima, S., Hosoda, K., Yoshida, S., Ito, N.: Carcinogenicity of 8-nitroquinoline in Sprague-Dawley rats. Cancer Lett, 4: 265-270, 1978.

6. Shirai, T., Miyata, Y., Nakanishi, K., Murasaki, G., Ito, N.: Hepatocarcinogenicity of polychlorinated terphenyl (PCT) in ICR mice and its enhancement by hexachlorobenzene (HCB). Cancer Lett, 4: 271-275, 1978.

7. Shirai, T., Takahashi, M., Fukushima, S., Tatematsu, M., Hirose, M., Ito, N.: Induction of preneoplastic hyperplasia and carcinoma by N-methyl-N’-nitrosoguanidine from regenerated mucosa of ulcers induced by iodoacetamide in fundus of rat stomach. Gann, 69: 361-366, 1978.

8. Nakanishi, K., Fukushima, S., Shibata, M., Shirai, T., Ogiso, T., Ito, N.: Effect of phenacetin and caffeine on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 69: 395-400, 1978.

9. Tatematsu, M., Cohen, SM., Fukushima, S., Shirai, T., Shinohara, Y., Ito, N.: Neovascularization in benign and malignant urinary bladder epithelial proliferative lesions of the rat observed in situ by scanning electron microscopy and autoradiography. Cancer Res, 38: 1792-1800, 1978.

10. Takahashi, K., Kawazoe, Y., Tada, M., Tada, M., Ito, N., Okada, M.: Carcinogenicity of 4-nitrosoquinoline 1-oxide and its possible role in carcinogenesis by 4-nitroquinoline 1-oxide. Gann, 69: 499-505, 1978.

11. Arai, H., Shirai, T., Hananouchi, M., Hirose, M., Murasaki, G., Ito, N.: Effect of protease inhibitors in mice treated with the hepatocarcinogen, hexachlorocyclohexane (α-isomer) and the bladder carcinogen, N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 69: 593-595, 1978.

12. Sato, K., Takaya, S., Imai, F., Hatayama, I., Ito, N.: Different deviation patterns of carbohydrate-metabolizing enzymes in primary rat hepatomas induced by different chemical carcinogens. Cancer Res, 38: 3086-3093, 1978.

13. Murasaki, G., Nakanishi, K., Ito, N., Arai, M., Masuko, K.: Electron microscopic observation of the liver in Dubin-Johnson syndrome. J Clin Electron Microscopy, 11: 5-6, 1978.

14. Tsuda, H., Takahashi, M., Murasaki, G., Ogiso, T., Tatematsu, M.: Effect of 3-amino-1H-1,2,4-triazole or low iodine diet on rat thyroid carcinogenesis induced by ethylenethiourea. Nagoya Med J, 23: 83-92, 1978.

15. Cohen, SM., Fukushima, S., Tsuda, H., Murasaki, G., Ito, N.: Effect of azathiopurine and OK-432 on urinary bladder carcinogenesis in rats. Gann, 69: 773-779, 1978.

16. Kawazoe, Y., Ogawa, O., Takahashi, K., Sawanishi, H., Ito, N.: Synthesis of 4-(N-hydroxy-N-methylamino)quinoline 1-oxide and its carcinogenic activity on mice. Gann, 69: 835-837, 1978.

17. Miyata, Y., Tsuda, H., Matayoshi-Miyasato, K., Fukushima, S., Murasaki, G., Ogiso, T., Ito, N.: Effect of vitamin A acetate on urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats. Gann, 69: 845-848, 1978.

18. Ito, N., Shirai, T., Miyata, Y.: Production of urinary bladder tumors by administration of N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) to pregnant, nursing and newborn rats. In: Severi, L.(ed.) Tumours of Early Life in Man and Animals, pp495-503. Perugia, Monteluce, Italy: Perugia Quadrennial International Conferences on Cancer, Perugia, Italy, 1978.

19. 伊東信行, 高橋道人：発がん性. トキシコロジー. 毒理学の基本的問題点とその実際, pp1220-1230, 地人書館, 1978.

20. 伊東信行：前がん状態を考える. がん予防の一面. 蟻塔, 24: 8-11, 1978.

21. 伊東信行, 立松正衛：化学的発癌の寄与するもの. 癌の疾患モデルとは何か. 蛋白質 核酸 酵素, 23: 469-479, 1978.

22. 伊東信行, 立松正衛：化学発癌における前癌病変. 日本臨牀, 36: 1150-1151, 1978.

23. 木下垣：Quinoline による肝腫瘍発生とその特性に関する実験病理学的研究. 名古屋市立大学医学会雑誌, 29: 93-111, 1978.

24. 村崎元五：膀胱癌発生過程の経時的変化とくにその前癌変化に関する実験的研究. 名古屋市立大学医学会雑誌, 29: 112-127, 1978.

25. 伊東信行：化学物質の癌原性検索法. テスト法 (2) 成熟囓歯類動物を用いる方法. 小田嶋成和, 橋本嘉幸 (編) 化学物質と癌の発生, pp33-43, 学会出版センター, 1978.

26. 白井智之, 高橋道人：癌原性物質誘発腫瘍の病理. 消化管 (2) 胃 (腺胃). 小田嶋成和, 橋本嘉幸 (編) 化学物質と癌の発生, pp179-200, 学会出版センター, 1978.

27. 福島昭治, 伊東信行：癌原性物質誘発腫瘍の病理. 尿路系臓器. 小田嶋成和, 橋本嘉幸 (編) 化学物質と癌の発生, pp247-264, 学会出版センター, 1978.

28. 板野龍光, 津田洋幸：癌原性物質誘発腫瘍の病理. 呼吸器系臓器. 小田嶋成和, 橋本嘉幸 (編) 化学物質と癌の発生, pp265-280, 学会出版センター, 1978.

29. 篠原良孝, 白井智之, 中西敬介, 広瀬雅雄, 高橋道人：睾丸悪性絨毛上皮腫の３例. 癌の臨床, 24: 853-857, 1978.

30. 中西敬介, 白井智之, 篠原良孝, 小木曽正, 村崎元五, 高野浩一, 山懸香：胃癌を合併した慢性リンパ性白血病 (C.L.L.) の１剖検例. 癌の臨床, 24: 1071-1075, 1978.

31. 伊東信行, 篠原良孝, 中西敬介：フェナセチン発癌. 臨床科学, 14: 1133-1136, 1978.

32. 伊東信行, 白井智之, 村崎元五：環境発癌物質と文献整理. とくに生体を用いての環境発癌物質の短期検索法について. 環境科学総合研究所年報, 6: 1-8, 1978.

1. Tatematsu, M., Cohen, SM., Fukushima, S., Shinohara, Y., Ito, N.: Vascular changes during rat urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 68: 127-128, 1977.

2. Nagao, M., Yahagi, T., Seino, Y., Sugimura, T., Ito, N.: Mutagenicities of quinoline and its derivatives. Mutation Res, 42: 335-342, 1977.

3. Tsuda, H., Miyata, Y., Murasaki, G., Kinoshita, H., Fukushima, S., Ito, N.: Synergistic effect of urinary bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine, N-[4-(5-nitro-2-furyl)-2-thiazolyl]- formamide, N-2-fluorenylacetamide, and 3,3′-dichlorobenzidine. Gann, 68: 183-192, 1977.

4. Tatematsu, M., Miyata, Y., Mizutani, M., Hananouchi, M., Hirose, M., Ito, N.: Summation effect of N-butyl-N-(4-hydroxybutyl)nitrosamine, N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide, N-2-fluorenyl- acetamide, and 3,3′-dichlorobenzidine on urinary bladder carcinogenesis in rats. Gann, 68: 193-202, 1977.

5. Shirai, T., Murasaki, G., Tatematsu, M., Tsuda, H., Fukushima, S., Ito, N.: Early surface changes of the urinary bladder epithelium of different animal species induced by N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 68: 203-212, 1977.

6. Tatematsu, M., Furihata, C., Hirose, M., Shirai, T., Ito, N., Nakajima, Y., Sugimura, T.: Changes in pepsinogen isozymes in stomach cancers induced in Wistar rats by N-methyl-N’-nitro-N-nitrosoguanidine and in transplantable gastric carcinoma (SG2B). J Natl Cancer Inst, 58: 1709-1716, 1977.

7. Fukushima, S., Hibino, T., Shibata, M., Murasaki, G., Ogiso, T., Ito, N.: Effect of hepatotoxic or nephrotoxic agents on the induction of colon cancers in rats by 1,2-dimethylhydrazine. Toxicol Appl Pharmacol, 40: 561-570, 1977.

8. Shinohara, Y., Miyata, Y., Murasaki, G., Nakanishi, K., Yoshimura, T., Ito, N.: Effect of N-(3,5-dichlorophenyl)succinimide on the histological pattern and incidence of kidney tumors induced by streptozotocin in rats. Gann, 68: 397-404, 1977.

9. Tatematsu, M., Shirai, T., Tsuda, H., Miyata, Y., Shinohara, Y., Ito, N.: Rapid production of hyperplastic liver nodules in rats treated with carcinogenic chemicals: A new approach for an in vivo short-term screening test for hepatocarcinogens. Gann, 68: 499-507, 1977.

10. Cohen, SM., Ichikawa, M., Bryan, GT.: Carcinogenicity of 2-(2-furyl)-3-(5-nitro-2-furyl)- acrylamide (AF-2) fed to female Sprague-Dawley rats. Gann, 68: 473-476, 1977.

11. Shirai, T., Cohen, SM., Fukushima, S., Ito, N.: Production of reversible papillary proliferation of the urinary bladder in rats. Gann, 68: 521-522, 1977.

12. Matsukura, N., Kawachi, T., Sasajima, K., Sano, T., Sugimura, T., Ito, N.: Induction of liver tumors in rats by sodium nitrite and methylguanidine. Z Krebsforsch, 90: 87-94, 1977.

13. Tsuda, H., Miyata, Y., Hagiwara, A., Hasegawa, R., Shirai, T., Ito, N.: Damage and repair of DNA in urinary bladder epithelium of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Gann, 68: 781-783, 1977.

14. Shinohara, Y., Ogiso, T., Hananouchi, M., Nakanishi, K., Yoshimura, T., Ito, N.: Effect of various factors on the induction of liver tumors in animals by quinoline. Gann, 68: 785-796, 1977.

15. Fukushima, S., Hibino, T., Shibata, M., Tsuda, H., Shirai, T., Takahashi, M., Ito, N.: Effect of iodoacetamide or Tween 60 on methyl-nitrosocyanamide carcinogenesis in rat glandular and forestomach. Gann, 68: 813-818, 1977.

16. Tatematsu, M., Ito, N.: Neovascularization in benign and malignant rat urinary bladder epithelial proliferative lesions observed by scanning electron microscopy of vascular casts. J Clin Electron Microscopy, 10: 5-6, 1977.

17. Furihata, C., Tatematsu, M., Shirai, T., Yokochi, K., Takahashi, M., Sugimura, T.: Pepsinogens and stomach cancer. In: Farber, E. et al. (eds.) Pathophysiology of Carcinogenesis in Digestive Organs, pp49-63: Univ of Tokyo Press, Tokyo, 1977.

18. 伊東信行, 津田洋幸, 白井智之：化学発癌物質の種類と発生方法・発生動物などの相互関係に関する文献的考察. 環境科学総合研究所年報, 4: 35-54, 1977.

19. 村崎元五, 広瀬雅雄, 立松正衛, 白井智之：DiGeorge 症候群の１剖検例. 小児科臨床, 30: 1281-1284, 1977.

20. 篠原良孝 : マイコトキシンのラット腎発癌におよぼす要因に関する実験的病理組織学的研究. 名古屋市立大学医学会雑誌, 28: 38-58, 1977.

21. 伊東信行：実験的尿路系腫瘍についての最近の知見. 臨床泌尿器科, 31: 853-869, 1977.