1989年

1. Shirai, T., Fukushima, S., Tagawa, Y., Okumura, M., Ito, N.: Cell proliferation induced by uracil-calculi and subsequent development of reversible papillomatosis in the rat urinary bladder. Cancer Res, 49: 378-383, 1989.

2. Thornton, M., Moore, MA., Ito, N.: Modifying influence of dehydroepiandrosterone or butylated hydroxytoluene treatment on initiation and development stages of azaserine-induced acinar pancreatic preneoplastic lesions in the rat. Carcinogenesis, 10: 407-410, 1989.

3. Hasegawa, R., Fukushima, S., Hagiwara, A., Masui, T., Masuda, A., Ito, N.: Long-term feeding study of N,N’-diphenyl-p-phenylenediamine in F344 rats. Toxicology, 54: 69-78, 1989.

4. Tsuda, H., Inoue, T., Asamoto, M., Fukushima, S., Ito, N., Okamura, T., Ohtaguro, K., Washida, H., Satoh, K., Amelizad, Z., Oesch, F.: Comparison of enzyme phenotypes in human bladder tumours and experimentally induced hyperplastic and neoplastic lesions of the rat urinary bladder. Virchows Arch B Cell Pathol, 56: 307-316, 1989.

5. Asamoto, M., Fukushima, S., Tatemoto, Y., Yamada, K., Fukui, S., Mori, M.: Immunohistochemical expression of keratin proteins in urinary bladder carcinoma. Pathol Res Pract, 184: 194-201, 1989.

6. Fukushima, S., Asamoto, M., Imaida, K., El-Bolkainy, MN., Tawfik, HN., Ito, N.: Comparative study of urinary bladder carcinomas in Japanese and Egyptians. Acta Pathol Jpn, 39: 176-179, 1989.

7. Ito, N., Fukushima, S.: Promotion of urinary bladder carcinogenesis in experimental animals. Exp Pathol, 36: 1-15, 1989.

8. Shirai, T., Nakamura, A., Fukushima, S., Takahashi, S., Ogawa, K., Ito, N.: Effects of age on multiple organ carcinogenesis induced by 3,2′-dimethyl-4-aminobiphenyl in rats, with particular reference to the prostate. Jpn J Cancer Res, 80: 312-316, 1989.

9. Ito, N., Hagiwara, A., Tamano, S., Kagawa, M., Shibata, MA., Kurata, Y., Fukushima, S.: Lack of carcinogenicity of quercetin in F344/DuCrj rats. Jpn J Cancer Res, 80: 317-325, 1989.

10. Tatematsu, M., Mutai, M., Aoki, T., de Camargo, JLV., Furihata, C., Ito, N.: Proliferation kinetics of pepsinogen altered pyloric gland cells in rats treated with N-methyl-N’-nitro-N-nitrosoguanidine. Carcinogenesis, 10: 907-911, 1989.

11. Shibata, MA., Hagiwara, A., Tamano, S., Ono, S., Fukushima, S.: Lack of a modifying effect by the diuretic drug furosemide on the development of neoplastic lesions in rat two-stage urinary bladder carcinogenesis. J Toxicol Environ Health, 26: 255-265, 1989.

12. Imaida, K., Tatematsu, M., Kato, T., Tsuda, H., Ito, N.: Advantages and limitations of stereological estimation of placental glutathione S-transferase-positive rat liver cell foci by computerized three-dimensional reconstruction. Jpn J Cancer Res, 80: 326-330, 1989.

13. Hagiwara, A., Tamano, S., Shibata, MA., Arai, M., Tsuda, H.: Lack of modifying effects of 2,2′-[(4-aminophenyl)imino]bisethanol sulfate on induction of preneoplastic γ-glutamyl transpeptidase-positive foci in a medium-term bioassay system using F344 rats. J Toxicol Sci, 14: 77-86, 1989.

14. Tatematsu, M., Katsuyama, T., Mutai, M., Asakawa, E., Ito, N.: Pyloric gland phenotypic expression of gastric cancers developing in the rat fundic glandular stomach. Carcinogenesis, 10: 1033-1039, 1989.

15. Shirai, T., Nakamura, A., Wada, S., Ito, N.: Pancreatic acinar cell tumors in rats induced by 3,2′-dimethyl-4-aminobiphenyl. Carcinogenesis, 10: 1127-1130, 1989.

16. Thamavit, W., Fukushima, S., Kurata, Y., Asamoto, M., Ito, N.: Modification by sodium L-ascorbate, butylated hydroxytoluene, phenobarbital and pepleomycin of lesion development in a wide-spectrum initiation rat model. Cancer Lett, 45: 93-101, 1989.

17. Hagiwara, A., Hirose, M., Miyata, Y., Fukushima, S., Ito, N.: Modulation of N-butyl-N-(4-hydroxybutyl)- nitrosamine-induced rat urinary bladder carcinogenesis by post-treatment with combinations of three phenolic antioxidants. J Toxicol Pathol, 2: 33-39, 1989.

18. Tagawa, Y., Shirai, T., Fukushima, S., Nakamura, A., Hirose, M., Ito, N.: Lack of modification by dietary unsaturated fat of 3,2′-dimethyl-4-aminobiphenyl-induced rat prostate and colon carcinogenesis. J Toxicol Pathol, 2: 49-53, 1989.

19. Ito, N., Imaida, K., Hasegawa, R., Tsuda, H.: Rapid bioassay methods for carcinogens and modifiers of hepatocarcinogenesis. Crit Rev Toxicol, 19: 385-415, 1989.

20. Shibata, MA., Yamada, M., Tanaka, H., Kagawa, M., Fukushima, S.: Changes in urine composition, bladder epithelial morphology, and DNA synthesis in male F344 rats in response to ingestion of bladder tumor promoters. Toxicol Appl Pharmacol, 99: 37-49, 1989.

21. Tada, M., Aoki, H., Kojima, M., Morita, T., Shirai, T., Yamada, H., Ito, N.: Preparation and characterization of antibodies against 3,2′-dimethyl-4-aminobiphenyl-modified DNA. Carcinogenesis, 10: 1397-1402, 1989.

22. Shibata, MA., Tamano, S., Kurata, Y., Hagiwara, A., Fukushima, S.: Participation of urinary Na+, K+, pH, and L-ascorbic acid in the proliferative response of the bladder epithelium after the oral administration of various salts and/or ascorbic acid to rats. Fd Chem Toxicol, 27: 403-413, 1989.

23. Asamoto, M., Fukushima, S., Tatemoto, Y., Yamada, K., Yuba, R., Mori, M.: Immunohistochemical evaluation of nonspecific cross reactive antigen and carcinoembryonic antigen (CEA) in urinary bladder carcinoma. Anticancer Res, 9: 319-326, 1989.

24. Hirose, M., Kurata, Y., Yamada, M., Shirai, T., Ito, N., Ohsawa, T.: Lack of modifying effects of linolic acid hydroperoxides and their secondary oxidative products on combined 7,12-dimethylbenz[a]anthracene and 1,2-dimethylhydrazine-initiated mammary gland, ear duct and colon carcinogenesis in female Sprague-Dawley rats. Cancer Lett, 47: 141-147, 1989.

25. Fukushima, S., Inoue, T., Uwagawa, S., Shibata, MA., Ito, N.: Co-carcinogenic effects of NaHCO3 on o-phenylphenol-induced rat bladder carcinogenesis. Carcinogenesis, 10: 1635-1640, 1989.

26. Shibata, MA., Yamada, M., Asakawa, E., Hagiwara, A., Fukushima, S.: Responses of rat urine and urothelium to bladder tumor promoters: possible roles of prostaglandin E2 and ascorbic acid synthesis in bladder carcinogenesis. Carcinogenesis, 10: 1651-1656, 1989.

27. Asamoto, M., Fukushima, S., Oosumi, H., Tatemoto, Y., Mori, M.: Immunohistochemical distribution of epithelial membrane antigen in bladder carcinomas as detected with a monoclonal antibody. Urol Res, 17: 273-277, 1989.

28. Asamoto, M., Fukushima, S., Horike, H., Tatemoto, Y., Mori, M.: Involucrin expression in urinary bladder carcinoma. Urol Res, 17: 279-283, 1989.

29. Kurata, Y., Tamano, S., Shibata, MA., Hagiwara, A., Fukushima, S., Ito, N.: Lack of carcinogenicity of magnesium chloride in a long-term feeding study in B6C3F1 mice. Fd Chem Toxicol, 27: 559-563, 1989.

30. Hirose, M., Yamaguchi, S., Fukushima, S., Hasegawa, R., Takahashi, S., Ito, N.: Promotion by dihydroxybenzene derivatives of N-methyl-N’-nitro-N-nitrosoguanidine-induced F344 rat forestomach and glandular stomach carcinogenesis. Cancer Res, 49: 5143-5147, 1989.

31. Asamoto, M., Tsuda, H., Kagawa, M., de Camargo, JLV., Ito, N., Nagase, S.: Strain differences in susceptibility to 2-acetylaminofluorone and phenobarbital promotion on rat hepatocarcinogenesis in a medium-term assay system: Quantitation of glutathione S-transferase P-positive foci development. Jpn J Cancer Res, 80: 939-944, 1989.

32. Hasegawa, R., Mutai, M., Imaida, K., Tsuda, H., Yamaguchi, S., Ito, N.: Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver. Jpn J Cancer Res, 80: 945-951, 1989.

33. Satoh, K., Hatayama, I., Tateoka, N., Tamai, K., Shimizu, T., Tatematsu, M., Ito, N., Sato, K.: Transient induction of single GST-P positive hepatocytes by DEN. Carcinogenesis, 10: 2107-2111, 1989.

34. Ito, N., Hirose, M.: Antioxidants. Carcinogenic and chemopreventive properties. Adv Cancer Res, 53: 247-302, 1989.

35. Tatematsu, M., Mutai, M., Inoue, K., Ozaki, K., Furihata, C., Ito, N.: Synergism between sodium chloride and sodium taurocholate and development of pepsinogen-altered pyloric glands: Relevance to a medium-term bioassay system for gastric carcinogens and promoters in rats. Jpn J Cancer Res, 80: 1035-1040, 1989.

36. Asamoto, M., Tsuda, H., Kato, T., Ito, N., Masuko, T., Hashimoto, Y., Nagase, S.: Strain differences in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of hepatocarcinogenesis: Immunohistochemical analysis of cytochrome P-450 isozyme induction by 2-acetylaminofluorene and phenobarbital. Jpn J Cancer Res, 80: 1041-1046, 1989.

37. Shibata, MA., Tanaka, H., Yamada, M., Tamano, S., Fukushima, S.: Proliferative response of renal pelvic epithelium in rats to oral administration of ortho-phenylphenol, sodium ortho-phenylphenate and diphenyl. Cancer Lett, 48: 19-28, 1989.

38. Yamaguchi, S., Hirose, M., Fukushima, S., Hasegawa, R., Ito, N.: Modification by catechol and resorcinol of upper digestive tract carcinogenesis in rats treated with methyl-N-amylnitrosamine. Cancer Res, 49: 6015-6018, 1989.

39. Hirose, M., Kagawa, M., Ogawa, K., Yamamoto, A., Ito, N.: Antagonistic effect of diethylmaleate on the promotion of forestomach carcinogenesis by butylated hydroxyanisole (BHA) in rats pretreated with N-methyl-N’-nitro-N-nitrosoguanidine. Carcinogenesis, 10: 2223-2226, 1989.

40. Hosokawa, S., Tatematsu, M., Aoki, T., Nakanowatari, J., Igarashi, T., Ito, N.: Modulation of diethylnitrosamine-initiated placental glutathione S-transferase positive preneoplastic and neoplastic lesions by clofibrate, a hepatic peroxisome proliferator. Carcinogenesis, 10: 2237-2241, 1989.

41. Ito, N., Hirose, M., Shibata, MA., Tanaka, H., Shirai, T.: Modifying effects of simultaneous treatment with butylated hydroxyanisole (BHA) on rat tumor induction by 3,2′-dimethyl-4-aminobiphenyl, 2,2′-dihydroxy-di-n-propylnitrosamine and N-methylnitrosourea. Carcinogenesis, 10: 2255-2259, 1989.

42. de Camargo, JLV., Tsuda, H., Tatematsu, M., Rodrigues, MAM., Yamada, M.,Tzuji, K., Ito, N.: Placental form of glutathione S-transferase in normal and diseased human uterine cervical mucosa. Carcinogenesis, 10: 2317-2320, 1989.

43. Saito, K., Nakagawa, S., Yoshitake, A., Miyamoto, J., Hirose, M., Ito, N.: DNA-adduct formation in the forestomach of rats treated with 3-tert-butyl-4-hydroxyanisole and its metabolites as assessed by an enzymatic 32P-postlabeling method. Cancer Lett, 48: 189-195, 1989.

44. Fitzgerald, DJ., Mesnil, M., Oyamada, M., Tsuda, H., Ito, N., Yamasaki, H.: Changes in gap junction protein (connexin 32) gene expression during rat liver carcinogenesis. J Cell Biochem, 41: 97-102, 1989.

45. Ito, N., Tatematsu, M., Hasegawa, R., Tsuda, H.: Medium-term bioassay system for detection of carcinogens and modifiers of hepatocarcinogenesis utilizing the GST-P positive liver cell focus as an endpoint marker. Toxicol Pathol, 17: 630-641, 1989.

46. Tatematsu, M., Ozaki, K., Mutai, M., Shichino, Y., Furihata, C., Ito, N.: Enhancing effects of various gastric carcinogens on development of pepsinogen-altered pyloric glands in rats. Carcinogenesis, 11: 1975-1978, 1989.

47. Ito, N., Fukushima, S., Hasegawa, R.: Bladder Cancers. Their process of development and its modification. Acta Pathol Jpn, 39: 1-14, 1989.

48. Ward, JM., Tsuda, H., Tatematsu, M., Hagiwara, A., Ito, N.: Hepatotoxicity of agents that enhance formation of focal hepatocellular proliferative lesions (putative preneoplastic foci) in a rapid rat liver bioassay. Fundam Appl Toxicol, 12: 163-171, 1989.

49. Ito, N., Tsuda, H., Hasegawa, R., Tatematsu, M., Imaida, K., Asamoto, M.: Medium-term bioassay models for environmental carcinogens. Two-step liver and multi-organ carcinogenesis protocols. In: Travis, CC. (ed.) Biologically-Based Methods for Cancer Risk Assessment, pp209-230. Plenum Publishing Co., 1989.

50. Shirai, T., Ito, N.: Rat prostatic carcinogenesis induced by 3,2′-dimethyl-4-aminobiphenyl. In: Karr, JP. & Yamanaka, H. (eds.) Prostate cancer. The Second Tokyo Symposium, pp77-85: Elsevier Sci. Pub. Co. Inc., 1989.

51. 伊東信行, 北川知行, 林裕造, 小林博:癌を語る. 動物発癌実験の目指すもの. Oncologia, 22: 39-47, 1989.

52. 津田洋幸:B6C3F1 マウス肝腫瘍における癌遺伝子活性と発癌性評価. 医学のあゆみ, 148: 598, 1989.

53. 白井智之, 高橋智, 伊東信行:剖検症例における前立腺肥大症と潜在癌. 泌尿器外科, 2: 221-225, 1989.

54. 伊藤 寛, 堀内格, 坂上充志, 本多英邦, 荻野高敏, 渡辺勇, 田内胤泰, 有坂吉彰, 福島昭治:膵の Solid and cystic tumor の1例. 胆と膵, 10: 687-694, 1989.

55. 伊東信行:化学発癌物質. 医学のあゆみ, 150: 32, 1989.

56. 萩原昭裕, 玉野静光, 倉田靖, 柴田雅朗:ラット・マウスの自然発生腫瘍: 甲状腺, 上皮小体および膵島. J Toxicol Pathol, 2: 73-83, 1989.

57. 乾正彦:各種胆汁酸の発癌修飾作用に関する実験的研究. 名古屋市立大学医学会雑誌, 40: 403-427, 1989.

58. 倉田靖:ラット肝および腎腫瘍発生に及ぼすアセトアミノフェンとその関連化合物の修飾作用についての実験的解析. 名古屋市立大学医学会雑誌, 40: 429-448, 1989.

59. 倉田靖, 萩原昭裕, 玉野静光, 柴田雅朗, 田中光, 山田真弓, 伊藤初美, 福島昭治:Beraprost sodium (TRK-100) のF344ラットを用いたN-methyl-N-nitrosourea(MNU) 多臓器発癌に及ぼす修飾作用. J Toxicol Sci, 14: 1-39, 1989.

60. 伊東信行, 広瀬雅雄, 増田あつ子, 長谷川良平:酸化防止剤の発癌性. 代謝, 26: 13-19, 1989.

61. 高橋智, 朝元誠人, 小川久美子, 福島昭治, 山本和英, 小笠原哲也:マクロアミラーゼ血症を合併した肺大細胞癌の1剖検例. 現代医学, 37: 299-305, 1989.

62. 立松正衛:魚の焼け焦げと癌. 内科, 64: 986, 1989.

63. 福島昭治, 白井智之:加齢と癌の発生. Mebio Interface, 6: 152-153, 1989.

64. 福島昭治:食べ物と発癌物質. プライマリ・ケアの医療 108, 1989.

65. 伊東信行:化学発癌モデルからみた前癌病変. 第86回日本医学会シンポジウム記録集 6-13, 1989.

66. 中園智昭, 柿原秀敏, 山本理佳, 加藤作郎, 福島昭治, 伊奈康孝, 山本正彦:Idiopathic bronchiolitis obliterans organizing pneumonia の1例. 名古屋市立病院紀要, 12: 33-38, 1989.

67. 伊藤寛, 堀内格, 坂上充志, 山下年成, 本多英邦, 荻野高敏, 渡辺勇, 高橋智, 福島昭治:機能性腸閉塞症が疑われた新生児腸閉塞症の1例. 名古屋市立病院紀要, 12: 71-74, 1989.

68. 辻村隆介, 森永正文, 平田修, 小池晧弌,高橋智, 福島昭治:短期間に見られた子宮肉腫の2例. 名古屋市立病院紀要, 12: 121-125, 1989.

69. 立松恵子:細胞形質発現を指標としたヒトおよびラット胃癌発生の解析. 名古屋市立大学医学会雑誌, 40: 55-78, 1989.